A study was carried out on 57 patients with chronic renal failure in a hospital in Kerman city, Islamic Republic of Iran. Blood samples were taken before and after haemodialysis to measure blood urea nitrogen and serum creatinine, triiodothyronine (T3) and thyroxine (T4) levels. Findings revealed that before dialysis T4 in 11 cases and T3 in 29 cases were lower than the normal range, but after ...

All but a few studies concerned with the peripheral metabolism of labeled thyroxine 1 in man have ignored the early phase of equilibration of labeled with unlabeled hormone in the tissues (see review in reference 1). Lennon, Engbring, and Eng-strom (2) measured the rate of disappearance of radioactivity from the blood during the initial 50 minutes after intravenous injection of T4-131I in human...

The EMIT homogeneous enzyme immunoassay for the determination of thyroxine (T4) was adapted to an automatic analyser (Type Kem-O-Mat) and compared with a conventional radioimmunoassay. Sera from 92 patients whose thyrometabolic status was being examined, and control sera with 3 different T4 concentrations were analysed by both methods. Day-to-day analyses of the control sera gave variation coef...

1. The effect of yohimbine (Y) on blood levels of thyroxine (T4), triiodothyronine (T3), and cortisol was investigated in 5 mature male white-tailed deer immobilized with xylazine hydrochloride (X). 2. T4 levels were erratic in X-treated deer, but stabilized in the X- and Y-treated deer. 3. T3 remained unchanged in both groups. 4. Cortisol levels have increased in X-treated deer, but declined i...

Human and rat placental homogenates convert L-thyroxine (T4) to 3,5,3'-L-triiodothyronine (T3) via a pathway termed type II iodothyronine deiodination. To study regulation of this pathway, cell dispersions were prepared from human placental chorionicdecidual membrane. Dispersed cells deiodinated T4 and 3,3',5'triiodothyronine (rT3), but not T3, at the 5' position. The reaction was only slightly...

GOAL To investigate the correlation between TSH and HbA1c in the treatment of L-thyroxine in the process of glycemic control in patients with subclinical hypothyroidism. PATIENTS AND METHODS The sample consisted of 100 patients, mean age 51.75±3.23 years, BMI=27.97±4.52 kg/m(2), with SH (TSH>4.2 mU/L and normal serum T3 and T4). Laboratory diagnosis included the determination of free T3, free...

SH is defined as a serum thyroid stimulating hormone (TSH) above the upper limit of the reference range, with a serum T4 and T3 thyroxine within the reference range. Other causes of a raised TSH such as a past history of thyroid disease and patients on T4 hormone treatment need to be excluded. Although patients with subclinical thyroid disease are usually asymptomatic, but nearly 30% have sympt...

Thyrotoxicosis has long been known to accelerate bone turnover and thus increase the risk for developing osteoporosis, especially in periand postmenopausal women. Increasingly sophisticated tests of thyroid function have indicated that minor degrees of hyperthyroidism are common in patients taking thyroxine (T4) therapy. Recent reports have suggested that women taking TSH-suppressive doses of T...

The diagnosis of thyroid disease now often can be achieved reliably by measuring thyrotropin (TSH) alone. Thyroxine (T4), triiodothyronine, and other analytes are only needed if TSH and the accompanying clinical condition are discordant. We describe here work that confirms the age independence of TSH in both inpatient and outpatient euthyroid hospital populations between ages 20 and at least 80...

To assess the most efficient means of monitoring thyroid status in an epilepsy clinic, total thyroxine (T4), free thyroxine stimulating hormone (TSH) were measured in 71 adult patients treated long-term with either phenytoin (DPH), carbamazepine (CBZ) or sodium valproate (VAL). Twenty-seven patients with one or more abnormal thyroid hormone results were further investigated by a thyrotrophin re...