نتایج جستجو برای: thyrotropin
تعداد نتایج: 9159 فیلتر نتایج به سال:
Haye et al. [ 1,2] have described previously a phosphatidylinositol-specific phospholipase A1 in thyroid homogenates which is stimulated by thyrotropin, and have suggested a role for it in the release of arachidonic acid for prostaglandin synthesis. They did not, however, clearly identify all the products formed after PI degradation. The release of free fatty acid from PI can also be effected b...
BACKGROUND It has been hypothesized that thyroid function may influence cancer risk, but few studies with adequate statistical power have investigated this question, and the results have not been consistent. METHODS In a prospective study of 29,691 people (19,710 women and 9,981 men) without previously known thyroid disease, thyrotropin was measured at baseline, and cancer incidence was recor...
Prevalence of thyroid dysfunction and its impact on cognition in older people has been demonstrated, but many points remain unclarified. In order to study the effect of aging on the thyroid gland, we compared the thyroid gland of very old mice with that of younger ones. We have first investigated the changes of thyroid microstructure and the possibility that molecules involved in thyroid functi...
CONTEXT Patients treated with levothyroxine typically ingest it in a fasting state to prevent food impairing its absorption. The serum thyrotropin concentration is the therapeutic index of levothyroxine action. OBJECTIVE The study objective was to determine the effect of the timing of levothyroxine administration in relationship to food on serum thyrotropin levels. DESIGN Participants were ...
Background: Angiotensin-converting enzyme 2 (ACE2) is a receptor for SARS-CoV-2, expressed in many organs’ cells, including the thyroid gland. Therefore, COVID-19 may influence gland function. Objectives: In this article, we aimed to investigate function patients and compare them healthy society indicate whether hormones level differ disease or not. Methods: This single-center retrospective cas...
BACKGROUND It is not clear whether the administration of radioiodine provides any benefit to patients with low-risk thyroid cancer after a complete surgical resection. The administration of the smallest possible amount of radioiodine would improve care. METHODS In our randomized, phase 3 trial, we compared two thyrotropin-stimulation methods (thyroid hormone withdrawal and use of recombinant ...
BACKGROUND The association between tobacco smoking and thyroid function is incompletely understood. METHODS In a cross-sectional, population-based study conducted between August 15, 1995, and June 18, 1997, of 20 479 women and 10 355 men without previously known thyroid disease, we calculated the geometric mean serum concentration of thyrotropin and the prevalence of hypothyroidism and hypert...
OBJECTIVES To assess the incidence of hypothyroidism after hemithyroidectomy and to identify risk factors for the development of hypothyroidism. DESIGN Retrospective analysis. SETTING A tertiary care academic medical center. PATIENTS The study included 90 patients who underwent a hemithyroidectomy from 1999 to 2004. MAIN OUTCOME MEASURES Hypothyroidism was defined as a serum thyrotropin...
OBJECTIVE To evaluate the relative importance of thyroid hormones and human chorionic gonadotropin in relation to the risk of gestational thyrotoxicosis in Saudi women living in Jeddah, Kingdom of Saudi Arabia. METHODS A prospective study was conducted on Saudi healthy pregnant women (N=406) at 12-15 weeks of gestation and compared with healthy non-pregnant controls (N=200). Maternal serum le...
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