Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT) presents with focal or diffuse nonenhancing MR imaging abnormalities in 50% of patients with SREAT during subacute exacerbation. Vasculitic changes in biopsy studies as well as the elevation of antithyroid antibodies and CSF protein suggests an inflammatory cause. We report the case of a patient with SREAT with cha...

Autoimmune diseases of the thyroid gland (ADTG) which include, Graves' disease, Hashimoto thyroiditis, primary hypothyroidism with atrophic thyroiditis, postpartum thyroiditis and 'silent' thyroiditis, are characterized by the presence of serum thyroid autoantibodies (TAB). Thyroid autoantibodies are not rare even in the general population of all ages, and their presence in women is 5 times mor...

MATHEMATICAL MODELING AND DYNAMICAL ANALYSIS OF THE OPERATION OF THE HYPOTHALAMUS – PITUITARY – THYROID (HPT) AXIS IN AUTOIMMUNE (HASHIMOTO’S) THYROIDITIS Balamurugan Pandiyan, B.S., M.S. Marquette University, 2011 This thesis is a mathematical modeling study of the operation of the negative feedback control through the hypothalamus-pituitarythyroid (HPT) axis in autoimmune (Hashimoto’s) thyroi...

Background: Mild eye signs, especially itchiness and grittiness of the eyelids and upper eyelid retraction (UER), are found in about 25% of patients with Hashimoto’s thyroiditis (HT) in whom antibodies against calsequestrin and flavoprotein (Fp) are often detected. The role of T lymphocyte reactivity against eye muscle antigens in patients with thyroiditis has not been investigated. Methods: We...

Irfan Yavaşoğlu 4.8.2008 Editor: The article entitled “Anti-thyroid antibodies and thyroid dysfunction in rheumatoid arthritis (RA): prevalence and clinical value” written by Atzeni et al. [1] and published in one of the recent issues of your journal was quite interesting. Here, we would like to emphasize some points. RA is a chronic inflammatory autoimmune disorder that affects approximately 0...

Rheumatoid arthritis (RA) and autoimmune diseases of the thyroid gland (AITD) often occur together. As diseases, they share common pathological pathways, reflecting fact that treatment underlying disease can influence course disorders. The pharmacotherapy RA is based on supply disease-modifying anti-inflammatory drugs with an increasing focus biologics. This article aims to review available lit...

Hashimoto’s encephalopathy (HE) is a rare disorder first characterized by Brain et al. in 1966 [1]. With only a few hundred reported cases, its etiology is not entirely understood but is believed to be related to the autoimmune mechanism of Hashimoto’s thyroiditis. Generally, patients diagnosed with HE demonstrate a progressive encephalopathy in the setting of elevated antithyroid antibodies. T...