Glycosylation is one of the most common posttranslational modification reactions and nearly half of all known proteins in eukaryotes are glycosylated. In fact, changes in oligosaccharides structures are associated with many physiological and pathological events, including cell growth, migration and differentiation, and tumor invasion. Therefore, functional glycomics, which is a comprehensive st...

discrepancy between pre & post treatment wbss (low dose & high dose, respectively) is reported. the aim of this study was determination the post-treatment wbs role in the diagnosis of lesions not identified by the pretreatment one. in this study 94 patients (pts) with dtc were evaluated. the results of pre & post treatment wbss were compared. overall, 25.6% of pts revealed more posi...

A 21-year-old male discovered that his thyroid gland was becoming enlarged in October 2008. Two months later, chest radiography during a routine physical examination revealed an abnormal shadow and he was referred to our hospital for a complete medical examination. He had experienced asthma-like wheezing about once a month for the past 2 years but he was not receiving any medication. He had smo...

The diffuse follicular variant of papillary thyroid carcinoma (DFV-PTC) is a rare malignant thyroid condition. It represents an uncommon variant of papillary carcinoma characterized by a diffuse involvement of thyroid parenchyma, follicular architecture and nuclear features of PTC in absence of a surrounding capsule. Up to date few data have been collected about this entity and, at the best of ...

The heart is an organ sensitive to the action of thyroid hormone, and measurable changes in cardiac performance are detected with small variations in thyroid hormone serum concentrations. Most patients with hyperthyroidism experience cardiovascular manifestations, and the most serious complications of hyperthyroidism occur as a result of cardiac involvement. Recent studies provide important ins...