OBJECTIVE: Due to the increased prevalence of thyroid dysfunction in subjects with type 2 diabetes and also this fact that antibodies could potentially identify subjects at risk of thyroid dysfunction, this study was conducted to investigate thyroid autoimmunity in type 2 diabetic patients. MATERIAL AND METHODS: Among patients referred to Yazd Diabetes Research Center, 4000 type 2 diabetic pat...

background and aims: 25-hydroxy vitamin d3 is recognized to be an essential element for healthy body; however, its deficiency has been identified as a risk factor for thyroid disease, diabetes mellitus and other autoimmune diseases and infectious diseases. thyroid disease is common in the general population that its prevalence increases proportional to age. subjects with poorly controlled diabe...

OBJECTIVE: Diabetes mellitus and thyroid disease are the two common endocrinopathies seen in adult population. Studies to evaluate thyroid disorders in patients with type 2 diabetes are lacking. The aim of this study was to compare prevalence of thyroid dysfunction and autoim-munity in type 2 diabetic patients with age and sex matched non-diabetic control group. MATERIAL AND METHODS: Among pat...

During the Islamic lunar month of Ramadan millions of Muslims abstain from drinking and eating from dawn to sunset. The objective of this study was to investigate the effect of intermittent Islamic fasting on reproductive function, hypothalamic-pituitary-thyroid axis and the peripheral metabolism of thyroid hormones in men. We measured serum levels of FSH. LH, testosterone, prolactin, FSH, T4...

A 38-y-old East Asian woman presented in 1985 with weight gain and cold intolerance. She was found to have a small goiter and an elevated thyroidstimulating hormone (TSH) level of 58 mU/l (normal range, 0.5–5). She was diagnosed with primary hypothyroidism and was treated with levothyroxine (L-T4) 0.1 mg/d. Her symptoms promptly improved. Between 1985 and 1993, she felt generally well. Her adhe...

CONTEXT The prevalence of abnormal thyroid function in the United States and the significance of thyroid dysfunction remain controversial. Systemic effects of abnormal thyroid function have not been fully delineated, particularly in cases of mild thyroid failure. Also, the relationship between traditional hypothyroid symptoms and biochemical thyroid function is unclear. OBJECTIVE To determine...

Thyroid is a one of the most important endocrine organs. Understanding the molecular mechanism underlying thyroid development and function, as well as thyroid diseases, is beneficial for the clinical treatment of thyroid diseases and tumors. Through genetic linkage analysis and exome sequencing, we previously identified an uncharacterized gene C14orf93 (RTFC, mouse homolog: 4931414P19Rik) as a ...

introduction : in order to evaluate the role of thyroid autoimmunity in patients with goiter, this study was done 10 years after implementation of iodine supplementation program ( iodised salt). the serum levels of thyroid peroxidase antibodies (anti tpo) and thyroglobulin antibodies (anti tg) were studied in a group of patients with simple goiter and compared with normal controls. materials an...

background: the phosphatidylinositol 3-kinase/akt signaling pathway is recognized as a key driver of cancer cell survival and proliferation, and is often contingent upon an impairment of expression/function of the pten tumor suppressor, a negative regulator of this pathway. in addition, the cytoskeletal signaling protein tensin 2 has also been implicated as a negative regulator of this pathway....

objective: due to the increased prevalence of thyroid dysfunction in subjects with type 2 diabetes and also this fact that antibodies could potentially identify subjects at risk of thyroid dysfunction, this study was conducted to investigate thyroid autoimmunity in type 2 diabetic patients. material and methods: among patients referred to yazd diabetes research center, 4000 type 2 diabetic pati...