DESIGN This was a retrospective clinical study. SETTING The study was conducted at a university-based tertiary cancer hospital. PATIENTS One hundred seven patients had initial thyroid cancer surgery and subsequent remnant radioiodine ablation. Patients underwent recombinant human TSH (rhTSH)-mediated diagnostic whole-body scan and rhTSH-stimulated thyroglobulin (Tg) measurement before April...

BACKGROUND The aim of this study was to determine the reference values for thyrotropin (TSH), thyroid hormones (total and free thyroxine, T4 and fT4; total and free triiodothyronine, T3 and fT3), thyroglobulin (Tg) and thyroid antibodies (thyroid peroxidase, TPOAb and thyroglobulin antibody, TgAb) in the population of the Republic of Srpska. METHODS A total of 250 euthyroid subjects were enro...

Objective We report a series of children with encephalopathy associated thyroid antibodies who are refractory to steroid monotherapy. Background Steroid Responsive Encephalopathy autoimmune thyroiditis (SREAT) is rare condition, only few isolated cases reported in children. Marked clinical improvement following treatment steroids, hallmark SREAT. Design/Methods An IRB approved chart review was ...

In general, the therapy of differentiated thyroid carcinoma (DTC), includes initial treatment and follow-up of patients. Nowadays, there is no universal accepted consensus regarding initial treatment of DTC patients. Several countries have their own guidelines and recommendations for treatment of DTC . Beside all controversies, mostly accepted recommendation regarding initial treatment of DTC i...

Background. In the follow-up of papillary thyroid cancer (PTC) patients treated with curative thyroidectomy and radioiodine ablation, raised thyroglobulin (Tg) predicts recurrence with reasonable sensitivity and specificity. However, a proportion of patients present with raised Tg level but no other clinical evidence of disease. Only limited data on Tg kinetics have been reported to date. Here ...

BACKGROUND The development of antibodies to thyroid peroxidase, thyroglobulin, and thyroid-stimulating hormone (TSH) receptor is a main feature of autoimmune thyroid diseases. OBJECTIVE To investigate whether complete removal of thyroid antigens results in the abatement of humoral thyroid autoimmunity. DESIGN Retrospective chart review study of patients treated and monitored with a standard...

Dear Editor, Case 1 was a 41-year-old man with history of primary hyperthyroidism. At the time diagnosis, thyroglobulin antibodies were elevated although no thyrotropin receptor (TRAB) available. The patient treated carbimazole for 20 months. cessation in May 2020, thyroid function and TRAB levels

BACKGROUND Though iodine deficiency in pregnancy is a matter of public-health concern, a functional measure of iodine status is lacking. The thyroid-specific protein thyroglobulin (Tg), which reflects thyroid size, has shown promise as a functional measure in studies of children and adults, but data in pregnancy are sparse. In a cohort of mildly to moderately iodine-deficient pregnant women, th...