نتایج جستجو برای: thiosemicarbazones
تعداد نتایج: 522 فیلتر نتایج به سال:
Chitosan oligosaccharide and high molecular weight crab shell chitosan were functionalized as imidazole-2-carboxaldehyde thiosemicarbazones their copper(II) complexes synthesized. The synthesized compounds characterized by FT-IR, 13C NMR, EPR spectroscopy, powder X-ray diffraction (PXRD) analysis, elemental analysis magnetic susceptibility measurements. low showed higher in vitro inhibitory act...
N(4)-phenyl substituted semicarbazones and thiosemicarbazones (1-4) of propiophenone and 4’methylacetophenone have been synthesized and characterized by spectrometrical methods analyses (IR, RMN H &C, SM). All compounds were evaluated for their in vitro trypanosomal activity against the bloodstream form of the strain 427 of Trypanosomabruceibrucei and have been tested on larvaeofbrine shrimp, A...
The present work reports on the synthesis, anti-Trypanosoma cruzi activities and docking studies of a novel series of 2-(pyridin-2-yl)-1,3-thiazoles derived from 2-pyridine thiosemicarbazone. The majority of these compounds are potent cruzain inhibitors and showed excellent inhibition on the trypomastigote form of the parasite, and the resulting structure-activity relationships are discussed. T...
Transition metal complexes of thiosemicarbazones have generated considerable interest due to their wide ranging biological activities. Zinc II complexes with thiosemicarbazone ligands were reported to posses antiproliferative, antitumor and antimicrobial activities. In this work, zinc (II) complex of 2-acetylbenzothiophene 3-thiosemicarbazone [Zn(BTTS)2] has been prepared by condensation of zin...
We synthesized a thiosemicarbazone-functionalized flavin (Fl-(H)TSC: 2-[2-(3,4-dihydro-7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10(2H)-yl)ethylidene]-hydrazinecarbothioamide) and its Pt(II) complex [Pt(Fl-TSC)(2)], and characterized it using X-ray diffraction, UV-visible absorption and luminescence spectroscopy. X-ray structural analysis for [Pt(Fl-TSC)(2)] revealed that the structure of the isoa...
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