نتایج جستجو برای: thiosemicarbazone
تعداد نتایج: 917 فیلتر نتایج به سال:
Experimental magnetic studies performed on the [{CuLX}2] system (HL = pyridine-2-carbaldehyde thiosemicarbazone, X Cl−, Br−, I−) point to larger electronegativity in X, lower magnitude of antiferromagnetic interactions. In order confirm this and other trends observed dip into them, computational (X Cl− (1), I− (2)) compounds are here reported. The chemical structural comparisons have been exten...
reaction of readily available 2-formyl -1-methyl-5-nitroimidazole (1) with 4-substituted-2-hydrazinothiazoles (2) afforded 2-formyl-l-methyl-5- nitroimidazole 4-substituted -2- thiazolylhydrazones (3). reaction of thiochromitn-4-one (4) with thiosemicarbazide gave thiochroman-4- one thiosemicarbazone (5). reaction of compound 5 with clc- haloaldehyde or ketones y ielded thiochroman--#-one 4-sub...
in the present study, quantitative relationships between molecular structure and anti-tubercular activity of some 5-methyl/trifluoromethoxy-1 h -indole-2,3-dione-3-thiosemicarbazone derivatives were discovered. the detailed application of an efficient linear method and principal component regression (pcr) for the evaluation of quantitative structure activity relationships of the studied compound...
SUMMARY 2-F o rmylpy rid i ne thiosemicarbazone (PT), 3-hydroxy-2-formylpyridine thiosemicarbazone (3-HP), and 5-hydroxy-2-formylpyridine thiosemicarbazone (5-HP) are potent inhibitors of the growth of Sarcoma 180 ascites cells. PT is quite toxic to the tumor-bearing host and does not markedly extend the lifespan of mice bearing Sarcoma 180; however, the therapeutic potential of 3-1-IP and 5-HP...
Zinc (II) complex, [Zn(25-MBTSC)2I2] (1), where (25-MBTSC = (E)-2-(2,5-dimethoxybenzaldehyde) thiosemicarbazone, has been synthesized from the reaction of ZnI2 with 25-MBTSC in methanol as solvent at 25 ºC. It was characterized by elemental analysis (CHN) and is confirmed by single-crystal X-ray diffraction analysis. The complex 1 crystallizes in a triclinic system, with space group P-ī, having...
The chelator di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT) shows potent and selective anticancer and antimetastatic activity. However, the mechanism by which it is initially transported into cells to induce cytotoxicity is unknown. Hence, the current investigation examined the cellular uptake of ¹⁴C-Dp44mT relative to two structurally related ligands, namely the aroylhydrazone ¹⁴...
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