The purpose of this study is to assess patients consulting full-time traditional health practitioners (THPs) and the practice of THPs after they had been trained on Human Immunodeficiency Virus (HIV)/ Sexually Transmitted Infections (STI) prevention and care. The sample included 222 patients interviewed when exiting a THP's practice (n=17) in purposefully chosen two urban sites in KwaZulu-Natal...

Thp present Royal Navy Officer selection system derives from the World War 2 developments in the British Armed Forces. At that time serious manpower WaJ problems, particularly in the Army, led to the experimental and then executive [Xa use of extended assessment systems, which embodied many of the elements of the I present day assessment centre (AC) approach. Although the most dramatic Innovati...

The role of neuronal histamine in memory processing. Neuronal histamine(HA) may play a role in memory processing. This hypothesis is based upon evidence that the action of histamine at central H1 and H2 histamine receptor sites has been shown to modulate memory of rats and mice in adversely-motivated tasks. The purpose of this study was to test this hypothesis more thoroughly in mice using two ...

INTRODUCTION The neuroendocrine histamine-secreting cell of the gastric fundus, the enferochromaffin-like cell, is the principal regulator of parietal cell acid secretion. We have proposed that histamine may regulate its own synthesis and release via an autocrine mechanism. The purpose of this study was to evaluate the role of the histamine receptor subtypes H1, H2 and H3 in the regulation of t...

In contrast to the corresponding mouse and rat orthologs, the human histamine H4 receptor (hH4R) shows extraordinarily high constitutive activity. In the extracellular loop (ECL), replacement of F169 by V as in the mouse H4R significantly reduced constitutive activity. Stabilization of the inactive state was even more pronounced for a double mutant, in which, in addition to F169V, S179 in the l...