The effects of three benzimidazole anthelmintics in dogs infected with a human strain of Strongyloides stercoralis were investigated. Cambendazole, but not thiabendazole or mebendazole, abrogated the subsequent development of a patent infection when administered at the same time as infection to immunocompetent dogs. None of the drugs eradicated infection when given after the onset of patency in...

Oesophagostomum bifurcum has recently been recognized as a common parasite of man in northern Togo and in Ghana. In a preliminary trial several anthelmintics were evaluated in the treatment of mixed Oesophagostomum and hookworm infections. Diagnosis was based on faecal culture, since the eggs of Oesophagostomum and hookworm cannot be distinguished morphologically. Of the anthelmintics tested, a...

INDIAN PEDIATRICS 392 VOLUME 42__APRIL 17, 2005 immunosuppressed individuals(2). A single oral dose of Ivermectin (200 μg/kg) has been reported to be more effective than multiple doses of thiabendazole(3). CVID is a syndrome characterized by hypogammaglobulinemia with phenotypically normal B cells(4). These patients are prone to infection with pyogenic organisms and also intestinal parasites, f...

Thiabendazole and benomyl were the most effective fungicides for the control of Diplodia natalensis Pole Evans stem-end rot, a major decay of early degreened fruit. This decay was also significantly reduced by imazalil and guazatine, but the level of control was not as consistent as that obtained with thiabendazole or benomyl. Control of Dip lodia stem-end rot was not obtained with DF-1OO or po...

Okinawa Prefecture is an endemic area of Strongyloides stercoralis infection. Since treatment of this infection remains unsatisfactory, we evaluated the efficacy of ivermectin. Twenty-three patients were treated with a single oral dose of ivermectin (mean +/- SD, 105.5 +/- 20.8 mcg/kg of body weight), followed by a second dose two weeks later. The rate of cure was 85.7% at 2 weeks after the fir...

The ability to stimulate the immune response of cattle and pigs offers a new means of disease intervention. This review discusses current in vivo experiments that have evaluated immunomodulators in cattle and pigs. Levamisole, thiabendazole, imuthiol, avridine, isoprinosine, bovine recombinant interferon, human recombinant interleukin-2, bovine recombinant interleukin-2 and various supplemental...