A new inhalation synchronised dosimeter triggered by low inspiratory flow rates has been assessed. The methacholine challenge test using dosimeter nebulisation with controlled tidal breathing was compared with continuous nebulisation using De Vilbiss No 40 nebulisers with deep inhalations in 11 asthmatic subjects. Within subject PD20 FEV1 values were lower with the dosimeter method than with th...

conclusions there was no statistically significant difference in the parotid absorbed dose between spiral tomography and a panoramic radiograph (p value = 0.18). the overall results of this study were similar to other studies. results for the tube side parotid, the average absorbed doses in spiral tomography of the anterior and posterior parts of the maxilla and mandible, with the 2 mm slice th...

PURPOSE To evaluate the suitability of the GD-301 glass dosimeter for use in in vivo dose verification in proton therapy. METHODS The glass dosimeter was analyzed for its dosimetric characteristic in proton beam. Dosimeters were calibrated in a water phantom using a stair-like holder specially designed for this study. To determine the accuracy of the glass dosimeter in proton dose measurement...

Radiation processing in many areas, particularly in radiation sterilization, demands control of the absorbed dose. Many dosimeters have been proposed for the high-level dose range (region of 10 to 50 kGy). However, in addition to the required reproducibility, reliability or uncertainty (< 5%), it is desirable for radiation processing that the selected dosimetric system is easy to operate. One o...

The ultimate check of the actual dose delivered to a patient in radiotherapy can only be achieved by using in vivo dosimetry. This work reports a pilot study to test the applicability of a thermoluminescent dosimetric system for performing in vivo entrance dose measurements in external photon beam radiotherapy. The measurements demonstrated the value of thermoluminescent dosimetry as a treatmen...

PURPOSE In optical-CT, the use of a refractively matched polyurethane solid-tank in place of a fluid bath has the potential to greatly increase practical convenience, reduce cost, and possibly improve the efficacy of flood corrections. This work investigates the feasibility of solid-tank optical-CT imaging for 3D dosimetry through computer simulation. METHODS A matlab ray-tracing simulation p...

Radiolabeled antibodies provide a potential basis for selective radiotherapy of human gliomas. We have measured tumor targeting by radiolabeled monoclonal antibodies directed against neuroectodermal and tumor-associated antigens in nude mice bearing human glioma xenografts. Monoclonal P96.5, a mouse IgG2a immunoglobulin, defines an epitope of a human melanoma cell surface protein and specifical...