During the ripening process of fruit, solubilization and depolymerization cell wall components takes place, which results in loss firmness or softening fruit. Recently, we reported that two different strawberry cultivars (“Cristal” “Portola”) exhibit differences their fruit values, with “Cristal” being firmest “Portola” softest. In present work, performed a comparative study changes physicochem...

Chitosan (CS) nanoparticles of thymoquinone (TQ) were prepared by the ionic gelation method and are characterized on the basis of surface morphology, in vitro or ex vivo release, dynamic light scattering, and X-ray diffractometry (XRD) studies. Dynamic laser light scattering and transmission electron microscopy confirmed the particle diameter was between 150 to 200 nm. The results showed that t...

Lalit Bhutani in the last issue of the U L (45:67) has noted the relative sparing of the underside of the chin and the circumocular region and the upper lip in lepromatous patients and the more severe involvement of the malar eminence, the forehead, and the chin. He attributes this variation to the possible effect of photosensitivity. Sabin (Arch. Neurol. 20 [March 1969]; and U L 37 [1969]) des...

Differential scanning calorimetry (DSC) and nuclear magnetic resonance (NMR) spectroscopy are applied to characterize the nonfreezable water molecules in fully hydrated D2O/sphingomyelin at temperatures below 0 degrees C. Upon cooling, DSC thermogram displays two thermal transitions peaked at -11 and -34 degrees C. The high-temperature exothermic transition corresponds to the freezing of the bu...

We describe the preparation and characterization of a glassy form of the moderately good glassformer PbGeO3, by mechanical damage, and compare its properties with those of the normal melt-quenched glass and the crystal. The damage-formed glass exhibits a DSC thermogram strikingly similar to that of a hyperquenched glass, implying that it forms high on the energy landscape. The final glass trans...

Thermograms obtained by differential scanning calorimetry of a range of bacteria of different heat resistances were compared. Equations were derived to calculate the rate at which the numbers of viable organisms in a calorimeter decline as the temperature is raised at a constant rate. Vegetative bacteria scanned at 10 degrees C min-1 showed multi-peaked thermograms with four major peaks (denote...

Stem cells based tissue engineering requires biocompatible materials, which allow the cells to adhere, expand, and differentiate in a large scale. An ideal biomaterial for clinical application should be free from mammalian products which cause immune reactivities and pathogen infections. We invented a novel biodegradable poly(L-lactic-co-ε-caprolactone)-sericin (PLCL-SC) copolymer membrane whic...

The conjugation of hydrophobic cytotoxic agents such as monomethyl auristatin E (MMAE) to the interchain sulfhydryl groups of monoclonal antibodies (Mabs) through a protease-labile linker generates a heterogeneous drug load distribution. The conjugation process can generate high-drug-load species that can affect the physical stability of antibody-drug conjugates (ADCs). In this study, the mecha...