introduction: oxygen is a drug and physician and nurses should be familiar with the effects and potential risks of oxygen therapy. the current study aimed to assess familiarity of physicians and nurses with various aspects of oxygen therapy. method: in this cross sectional study, the familiarity of physicians and nurses with various aspects of oxygen therapy in a teaching hospital was evaluated...

objective: antisocial, aggressive and delinquent behaviors in adults often begin early in life. basal cortisol is a valuable biological marker in children with disruptive behavior disorder (dbd). to investigate the association between biological factor (cortisol) and disruptive behaviors, we studied the effect of family training on salivary cortisol level in children with dbd. methods: basal sa...

objective: cytochrome p450 is one of the major drug metabolizing enzyme families and its role in metabolism of cancer drugs cannot be less emphasized. the association between single nucleotide polymorphisms (snps) in cyp1a1 and pathogenesis of chronic myeloid leukemia (cml) has been investigated in several studies, but the results observed vary based on varied risk factors. the objective of thi...

background after treatment cessation, a high prevalence of relapse was reported in chronic hepatitis b (chb) patients in china, especially in nucleot(s)ide analogues (nucs)-experienced patients. re-treatment for these patients remains unsolved. objectives this study aims to evaluate the efficacy of pegylated interferon in hbeag positive patients with exposure to antiviral therapy. patients and ...

context: to evaluate treatment success and hypothyroidism following main methods of radioiodine therapy of toxic nodular goiter (tng); calculated versus fixed dose and high versus low dose of radioiodine. evidence acquisitions: we searched medline and scopus databases from inception till july 2013, for clinical trials that compared two different methods of radioiodine administration in tng. the...

myelodysplastic syndromes (mds) are a group of hematological disorders ranging from chronic refractory anemia to leukemia. there are some reports about association of mds with autoimmune disorders and vasculitis. in this study we describe a patient with mds and vasculitis presenting with central nervous system (cns) involvement. a clinical response to immunosuppressive therapy was also observed...

reye's syndrome is defined as fatty liver degeneration and acute encephalopathy following diffused abnormal mitochondrial activity. we reported a two year old girl admitted with lethargy and meningismus despite no evidence of blood sugar decrease, history of previous viral disease or drug use, complete tests showed reye syndrome as the final diagnosis. conservative protocols and treatment inclu...

introduction: management of early relapsed or refractory lymphoma [hodgkin & non- hodgkin lymphoma (hl & nhl)] is a matter of problem, especially when hematopietic stem cell support is not available. the aim of this study was to evaluate effectiveness of iev regimen ( ifosfamide, epirubicin, vp16), in lymphoma patients who are not candidate for stem cell transplantation. because the majority of...

Introduction: Use of patient-based voice assessment scales is an appropriate method that is frequently used to demonstrate effectiveness of voice therapy. This study was aimed at determining the effectiveness ofvoice therapy among patients with secondary muscle tension dysphonia (MTD) and vocal mass lesions.   Materials and Methods: The study design was prospective, with within-participant repe...

Langerhans cell histiocytosis (LCH) is a rare disorder described as three different entities including eosinophilic granulomaof bone, the Hand-Schuller-Christian syndrome, and Letterer-Siwe disease. LCH is currently classified into singlesystem LCH, and multisystem LCH. Patients with single system LCH have an excellent prognosis, and are mostlytreated with local therapy. Multisystem LCH is subd...