Covalent stabilization of micelles and vesicles has attracted increasing attention in recent years. In particular, shell cross-linked (SCL) micelles are potentially useful nanosized vehicles for the delivery of various actives (e.g., drugs, fragrances, pesticides). The first example of SCL micelles was described by Wooley and co-workers, who oligomerized pendent styrene groups by using radical ...

IMPORTANCE Accurate measurements of choroidal thickness (CT) using enhanced-depth imaging optical coherence tomography (EDI-OCT) require a well-defined choroid-scleral junction (CSJ), which may appear in some eyes as a hyporeflective band corresponding to the suprachoroidal layer (SCL). OBJECTIVE To identify factors associated with the presence and thickness of the SCL in healthy participants...

Sucralose (SCL) is one of the most widely used edulcorants in world, including bychildren and adolescents, but its effects on metabolic programming are not sufficient andconclusive. In this study we evaluated whether ingestion SCL or sucrose (SUC) by youngrats interferes with parameters adult rat. We 21-day-old male wistarrats, which received pure water (control) added SUC SCL, until 60 days ag...

Blood and vascular cells are generated during early embryogenesis from a common precursor, the hemangioblast. The stem cell leukemia gene (SCL/tal 1) encodes a basic helix-loop-helix transcription factor that is essential for the normal development of blood progenitors and blood vessels. We have previously characterized a panel of SCL enhancers including the +19 element, which directs expressio...

The SCL (TAL1) transcription factor is a critical regulator of haematopoiesis and its expression is tightly controlled by multiple cis-acting regulatory elements. To elaborate further the DNA elements which control its regulation, we used genomic tiling microarrays covering 256 kb of the human SCL locus to perform a concerted analysis of chromatin structure and binding of regulatory proteins in...

The importance of the electron loss from the separate confinement layer (SCL) to the p-cladding in 1.5 μm lasers is analysed comparing two structures. One is a regular structure with strained InGaAsP quantum wells and a 1.15 μm emitting InGaAsP SCL and the second one incorporates an additional In0.81Ga0.19P electron stopper layer (about 50 meV high) at the interface between the p-cladding and t...

The Symptom Checklist - Post-Traumatic Stress Disorder Scale (SCL-PTSD), also known as Crime-Related PTSD Scale has been validated in survivors of interpersonal trauma in the general population. However, the psychometric properties have not been investigated in a clinical setting for patients with PTSD from diverse traumatic events. This study investigates the reliability and validity of the Ko...

About 50% of patients with the polymyositis/scleroderma (PM-Scl) overlap syndrome are reported to have autoantibodies to a nuclear/nucleolar particle termed PM-Scl. The particle is composed of several polypeptides of which two have been identified as autoantigens. In this report, human cDNA clone coding for the entire 75-kD autoantigen of the PM-Scl particle (PM-Scl 75) was isolated from a MOLT...

Spindle-cell lipoma (SCL) is a variant of lipoma, usually presenting in the neck or trunk. SCL of the oral cavity is rare. Some cases of oral SCL have been reported; however, the clinico-pathologic characteristics of oral SCL are still unknown. Here we report on 2 cases and review 33 cases of oral SCL published in the literature. The patients were 23 men and 12 women, with a mean age of 55 year...

The stem-cell leukemia (SCL, also known as TAL1) gene encodes a basic helix-loop-helix transcription factor that is essential for the initiation of primitive and definitive hematopoiesis, erythrocyte and megakarocyte differentiation, angiogenesis, and astrocyte development. Here we report that the zebrafish produces, through an alternative promoter site, a novel truncated scl (tal1) isoform, sc...