Understanding interactions at the polymer / metal oxide interface is central to improving performance lifetime of corrosion resistant coatings, where network polymers commonly form via step growth mechanisms in presence pigments. Here we employ a holistic analytical approach encompassing ATR-FTIR, DSC and molecular dynamics simulations consider how crosslinker structure affects adsorption incor...

We developed a competition-based screening strategy to identify compounds that invert the selective advantage of antibiotic resistance. Using our assay, we screened over 19,000 compounds for the ability to select against the TetA tetracycline-resistance efflux pump in Escherichia coli and identified two hits, β-thujaplicin and disulfiram. Treating a tetracycline-resistant population with β-thuj...

Many microorganisms produce molecules having antibiotic activity and expel them into the environment, presumably enhancing their ability to compete with their neighbours. Given that these molecules are often toxic to the producer, mechanisms must exist to ensure that the assembly of the export apparatus accompanies or precedes biosynthesis. Streptomyces coelicolor produces the polyketide antibi...

The aims of the current study were to detect the virulence factors and antibiotic resistance of Shiga toxin-producing E. coli, in animal milk and dairy products in Iran. After E. coli dentification with culture method, PCR assay were developed for detection of pathogenic genes, serotypes and antibiotic resistance genes of E. coli. Results showed that out of 719 samples, 102 (14.18%) were confir...

We describe an optimized system for the easy, effective, and precise modification of the Escherichia coli genome. Genome changes are introduced first through the integration of a 1.3 kbp Landing Pad consisting of a gene conferring resistance to tetracycline (tetA) or the ability to metabolize the sugar galactose (galK). The Landing Pad is then excised as a result of double-strand breaks by the ...

MAC it happen : Presented is a study of the synergistic structuredirecting effect of metal–amine complexes (MACs) with different chelating polyamine ligands and imidazolium-based ionic liquid (IL) cations. For the first time, a layered selenidostannate with an asymmetric eight-membered ring, an organic-decorated layered selenidostannate, and a 3D selenidostannate with both the MAC and IL cation...