نتایج جستجو برای: testis tissue
تعداد نتایج: 934342 فیلتر نتایج به سال:
We first identified genes differentially expressed in rodent testis by comparing total testis, (TT; gonads whose tunica was removed by decapsulation) and isolated seminiferous tubules (TU; lacking the interstitial cells) to enriched populations of Sertoli cells (SE), spermatogonia (SG), pachytene spermatocytes (SC) and round spermatids (ST). Chondrocytes (CC) and vascular smooth muscle (SM) sam...
The aim of the present study was to evaluate the roles of gonadotropin-inhibitory hormone (GnIH) as an endocrine link between increasing adiposity and impaired testicular function in mice. To achieve this, the effect of GnIH on changes in nutrients uptake and hormonal synthesis/action in the adipose tissue and testis was investigated simultaneously by in vivo study and separately by in vitro st...
In the present study, controlled burns of 1 testis have induced the formation of testis-specific antibodies in Hartley guinea pigs. The antibodies reacted with autologous as well as homologous testicular extracts. In addition, pathological changes have been noted in the germinal components of the contralateral testis, which were similar to those observed after the induction of experimental al...
Three members of a receptor tyrosine kinase family, including Tyro3, Axl, and Mer, are collectively called as TAM receptors. TAM receptors have two common ligands, namely, growth arrest specific gene 6 (Gas6) and protein S (ProS). The TAM-Gas6/ProS system is essential for phagocytic removal of apoptotic cells, and plays critical roles in regulating immune response. Genetic studies have shown th...
Background & Aims: Para-Nonylphenol (p-NP) is an estrogenic compound with toxic effects on the various organs including testis. The purpose of this investigation was to study the toxic effects of p-NP on the testis tissue of mice and evaluation of the effect of Nigella sativa oil (NSO) against this toxicity Materials & Methods: This study was conducted on 24 adult male NMRI mice (32&plu...
Background and objectives: Although anabolic androgenic steroids (AAS) use has become became more prominent in bodybuilders and professional athletes, their consumption is nowadays a problem that involves a wider population. Methandienone or dianabol is an anabolic androgenic steroid which is used by athletes for fitness. This study was conducted to investigate, the likely prot...
Background: Varicocele is a dilated vein of the pampiniform plexus that cause to det-rimental time-dependent effects so this study describes the effect of varicocele on the level of IL-6 and interferon gamma in serum and testis tissue, number of sertoli and spermatogonia cells, seminiferous tubules diameter and sperm activity in immature rats. Methods: Thirty six immature rats, 5-6 weeks aged ...
The aim of the present study was to explore the underlying mechanism and diagnostic potential of Ran‑binding protein M (RanBPM) in human spermatogenesis and oogenesis. RanBPM expression in human testis and ovaries was analysed using polymerase chain reaction (PCR) and western blotting, and immunofluorescence was performed on testis and ovary tissue sections during different developmental stages...
Objective(s): Bisphenol A (BPA) as a synthetic compound is applied in many plastic industries. BPA has been reported to have endocrine-disrupting feature with cytotoxic effects. The study aimed to evaluate the efficiency of Naringin against testicular toxicity induced by BPA in adult rats.Materials and Methods: The animals were assigned into six groups of control, BPA-treated (50 mg/kg), BPA+Na...
Background and Objective: Fenvalerate is a component of the pyrethroid pesticide induces oxidative stress. This study was done to determine the effect of garlic extract (GE) and N-acetylcysteine (NAC) against fenvalerate-induced oxidative stress in the serum and testis tissue of rat. Methods: In this experimental study, 42 Wistar rats were randomly allocated into 7 groups including: control gr...
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