abstract objective: previous studies have indicated the hyperglycemia-induce cell death in various tissues such as brain, kidneys, liver and especially in the testis. recent studies have reported that diabetes can trigger male infertility. in this study we report the histological analysis of the testis tissue after diabetes type 1 induction in wistar rats. materials and methods: at various time...

testicular chloroma is an unusual form of extramedullary acute myeloid leukemia. we present a rare case that after chemotherapy relapsed with the appearance of metachronous testicular chloroma and we suggest prophylactic radiotherapy.

conclusions buprenorphine is more suitable for treating opiate addiction in males since it does not affect normal testicular structure and function. results stereological analysis of rat testes showed no significant effect of methadone and buprenorphine administration on the testis volume (p > 0.05). however, microscopic stud­ies of rat tissues in the methadone-administered group showed atrophi...

background new research proposes the pluripotency of spermatogonial cells obtained from testis. these spermatogonia-derived stem cells are called embryonic stem-like cells that express embryonic stem cell markers and differentiate to the three germ layers. objectives the aim of the present study was to generate embryonic stem-like cells from neonatal mouse testis. materials and methods the test...

  SUMMARY With the aim of surgical epidemiology nature of undescended testis, we examined 8034 school age boys in the city of Tehran. We invatted affected persons to Loghman-e-Hakim Medical Center for repeated examination and further diagnostic in­vestigations, results are: Among 8034 persons 82 had undescended testis, it means 1 .02 % , 56 % are in the right, and 33%  in the left, 11 % are...

THE undescended testis is more susceptible to trauma (Gross and Jewett 1956) and to malignant change (Collins and Pugh, 1964; Altman and Malament, 1967) than the normally placed testis. It has been shown that degeneration in an ectopic testis begins at about the age of 5 years (Scorer 1967; Cohn 1967). It is therefore generally accepted that orchidopexy should be carried out at around the age o...

BACKGROUND Testicular torsion associated with undescended testis is uncommon but requires immediate treatment. Ultrasound Doppler is recognized as the preferred imaging modality for testicular torsion due to its high specificity, sensitivity and availability. OBJECTIVES To determine the accuracy of ultrasound Doppler in diagnosis of torsion of undescended testis. METHODS We describe three p...

OBJECTIVE To investigate the effects of continued hypoxia on postnatal development of the rat testis. DESIGN Wistar rats were exposed to simulated hypoxia from birth to postnatal day (PND) 45. Testosterone (T) in the plasma and the testis was measured in rats at PND 3, 7, 14, 21, 28, 35 and 45 respectively. Testis histology and cellular ultrastructure were studied. RESULTS a) Hypoxia induce...

BACKGROUND Nuclear protein in testis carcinoma is a rare and very aggressive undifferentiated cancer which characteristically arises in the midline of the head, neck, and mediastinum. CASE PRESENTATION We describe the case of a 46-year-old white woman admitted for superior vena cava syndrome revealing a mediastinal tumor. Pathological examination of specimens obtained by mediastinoscopy revea...

We have developed a new strategy for differential screening of genes that are expressed in two or more tissues, and have used it to identify genes that are preferentially expressed in both testis and ovary. In this approach, testis-specific cDNAs were first generated using the suppression subtractive hybridization technique, cloned and arrayed in microplates. The inserts from the subtracted tes...