Objective: To study the effect of Bicalutamide on testicular weight in adult rats. Study Design: Laboratory based randomized controlled trial. Place and Duration of Study: Anatomy Department, Armed Forces Postgraduate Medical Institute (AFPGMI), Rawalpindi, Pakistan in collaboration with National Veterinary Laboratories (NVL), Islamabad, Pakistan from April to May 2008. Material and Methods: Fo...

background: breast and testicular cancers affect a substantial and increasing proportion of the global population. self-examination encourages early detection and treatment of these cancers, which positively impacts on patient quality of life and survival. methods: the present study investigated the role of body esteem in breast and testicular self-examination. men ( n = 60) and women ( n = 90)...

Objective- Release of free radicals and oxidants following increased temperature of testis in cryptorchidism, play an important role in the producing testicular damage. The present study investigated the role of vitamin C as an antioxidant in protecting the testis against damage in experimental unilateral cryptorchidism. Design- Experimental study Animals- Forty five male adult Wistar–Albino ...

We performed a systematic review and critique of the literature on the frequency of undescended testis (UDT) among boys from birth to adolescence. Special attention was given to whether previous testicular position was taken into account to distinguish between congenital and acquired UDT. We searched Medline, Embase, Cinahl and the Cochrane Library. Any study reporting on the frequency of UDT w...

Kyung-Ok-Ko (KOK), a well-known traditional Korean medicinal formula, has long been used to invigorate the essential qi. This use of KOK may be associated with reproductive ability as a more modern concept. The protective effect of KOK was evaluated against deterioration of testicular function induced by heat exposure in male mice. Male fertility was disrupted by scrotal heat stress at 43°C for...

Bisphenol A (BPA) is an estrogenic environmental toxicant, a synthetic monomer widely used to polymerize polycarbonate plastics and resins. BPA has been implicated to have hazardous effect on reproductive health in human and experimental rats. Lycopene is a powerful antioxidant and potential high-value compound for the prevention of many diseases. The present study has been designed to investig...

Abstract Combinations of fructose- and fat-rich diets in experimental animals can model the human metabolic syndrome (MS). In rats, the increase in blood pressure (BP) after diet manipulation is sex related and highly dependent on testosterone secretion. However, the extent of the impact of diet on rodent hypophysial-testicular axis remains undefined. In the present study, rats drinking a 10% f...

BACKGROUND Anabolic androgenic steroids (AAS) is being used in medical treatments, but AAS also was identified to have the risks of adverse effects towards patients and consumers health. OBJECTIVE Present study was conducted to observe the effects of testosterone, nandrolone, and stanozolol (forms of AAS) intake during onset of puberty on the rat testicular histology. MATERIALS AND METHODS ...

Testicular integrity is compromised during illness or infection leading to temporary or permanent infertility and studies have associated elevated nitric oxide (NO) with infertility. This study was designed to investigate the effect of inhibiting nitric oxide synthase on nicotine-induced reproductive organ decrease in male rats. Forty-eight male Wistar rats (160-180g) were randomly assigned to ...

The objective was to determine the effects of a recombinant fusion protein anti-GnRH vaccine on testicular development, feedlot performance, and carcass quality of beef bulls. Crossbred beef bulls (n = 58, average weight 306 kg, 9 mo of age), were randomly allocated to two groups and received either an anti-GnRH vaccine (GnRH) or placebo (Control) by intramuscular injection on d 0, 56, and 112....