background: disruption of testicular function and arrest ofspermatogenesis are the consequence of cryptorchidism inresponse to elevated temperature. objectives:this investigationwas set to clarify the possible ghrelin efficacy in altering somesperm quality parameters upon experimentally-induced cryptorchidism.methods: thirty male adult rats were scheduled for thestudy and were divided into thre...

Age-related decline in male sex hormones is a direct consequence of testicular aging. These changes in the hormonal complement cause physiological disturbances affecting the quality of life for millions of aging men. To assess the influence on testicular aging of pituitary adenylate cyclase-activating peptide (PACAP), a polypeptide that regulates testicular steroidogenesis in vitro, we compared...

Total immunoglobulin G (IgG) in rat testicular interstitial fluid and serum was measured by two-site enzyme-linked immunosorbent assay, which displayed minimal cross-reactivity with IgA or IgM. Normal adult testicular fluid IgG concentrations (2.67 +/- 0.98 mg/ml) were found to be 65% of the levels found in serum. Disruption of seminiferous tubule function by experimental cryptorchidism had no ...

OBJECTIVE There are few studies of outcome in male patients with undefined 46 XY disorder of sex development (DSD). We aimed to assess testicular function and clinical characteristics after puberty in men with idiopathic 46 XY DSD. Design We conducted a University Hospital-based observational follow-up study. METHODS Nineteen patients with severe hypospadias associated with other signs of def...

 Abstract  Testicular torsion is a medical emergency appearing at any age, the prevalence of  which in the neonatal period comprises 10% of the whole cases occurring at any  point in life. Among all the cases being diagnosed at birth, 70% has occurred in the  prenatal period and 30% in the neonatal period. Generally, the most common symptoms  of testicular torsion during postnatal period includ...

BACKGROUND Copper is essential as a trace element for metabolic processes. Exposure to copper in industries develops toxicity among the workers. Previous findings on adverse effects of copper on male reproductive function in adult albino rats led to investigate the effects of this metal on reproductive function of maturing male rats in the present experiment. METHODOLOGY To study these effect...

Background: The objective of this study was to investigate the effect of high and moderate summer ambient temperatures on testicular structures and endocrine profile of developing ram lambs. Materials and Methods: Twenty fall-born ramlambswere randomly divided into two groups: animalswere kept outdoor (n=10) under ambient temperature (31-50°C) or maintained indoor (26-32°C) from May to October ...