Background: Obesity, physical inactivity, and altered estrogen metabolism play integrated role contributing to the disease risk profiles of postmenopausal women (PMW). Aim: To study the correlation of body fat and blood lipids with autonomic nervous system activity in PM Indian women. Subjects and Methods: A total of 60 PM sedentary women without any gross systemic disease were selected as a co...

Background: Type 2 diabetes mellitus (Type DM), characterized by a relative insulin deficiency or resistance, is associated with cluster of metabolic abnormalities, which includes glucose intolerance, hypertension, unique dyslipidemia, procoagulant state, and an increase in macrovascular diseases. Aims Objectives: The present study was conducted to correlate between fasting postprandial apolipo...

Technetium-labeled low density llpoprotelns (Tc-LDL) appear to be useful for describing LDL blodlstribution In normal and dysllpldemlc sub|ects. We Injected T c L D L Into subjects with large tendon xanthomas secondary to homozygous familial hypercholesterolemia or sttosterolemla. Rapid (4 hours) accumulation of Tc-99m activity In xanthomas was observed, and this accumulation Increased over a 2...

The wide variability in the biochemical expression of familial hypercholesterolemia (FH) is only partly explained by mutational heterogeneity in the low density lipoprotein receptor (LDLR) gene. In the current study, we measured this biochemical variability in a group of children heterozygous for the >15-kb LDLR gene deletion (n=67) and examined the contribution of apolipoprotein (apo) E and B ...

Abstract Objective: Diabetes mellitus is the most common metabolic disease. One of the most common problems in diabetic patients is atherosclerotic cardiovascular disease which is induced by hyperlipidemia. Impaired lipid metabolism resulting from uncontrolled hyperglycemia has been implicated in cardiovascular complications in diabetic patients. Also, glycated hemoglobin (HbA1c) has been rega...

Background: Although it is well known that dyslipidemia is the major risk factor for developing acute coronary syndrome (ACS) but its role in causing minor myocardial damage in unstable angina (UA) patients is rarely studied in south India, where obesity and dyslipidemia has been more common due to genetic and life style factors. Objective: The aim of our study was to find out the role of lipid...

OBJECTIVE To assess the efficacy of probiotic Lactobacillus on serum lipids using a meta-analysis of randomized, controlled trials. METHODS Fifteen studies containing 15 trials, with 976 subjects were included. The pooled WMD was calculated by random effects model. RESULTS Probiotic Lactobacillus consumption significantly reduced TC by 0.26mmol/l (95% CI, -0.40 to -0.12) and LDL-C by 0.23mm...

In order to determine the impact of garlic on total cholesterol (TC), TAG levels, as well as LDL and HDL, and establish if any variables have an impact on the magnitude of this effect, a meta-analysis was conducted. A systematic literature search of MEDLINE, CINAHL and the Cochrane Database from the earliest possible date through to November 2007 was conducted to identify randomised, placebo-co...

BACKGROUND Whole grains are recognized for their potential role in preventing cardiovascular diseases; however, results from randomized controlled studies on blood lipids are inconsistent, potentially because of compositional differences between individual grain types for some nutrients, including dietary fiber. OBJECTIVE Using a meta-analytic approach, we assessed the effect of whole-grain c...

Introduction: Obesity is a chronic disease and is a known risk factor for development of cardiovascular diseases (CVD), and its risk can be independently decreased through lifestyle modification. The aim of this study was to assess the effect of endurance training and hydroalcoholic extract of dill on biochemical cardiovascular risk factors in obese male rats. Materials and methods: Thirty-two...