نتایج جستجو برای: targeted nano contrast agent

تعداد نتایج: 814854  

2008
Furong Ye Eun-Kee Jeong Zhanjun Jia Tianxin Yang Dennis Parker Zheng-Rong Lu

A peptide targeted contrast agent, CLT1-(Gd-DTPA), was synthesized for molecular imaging of fibronectin-fibrin complexes in tumor tissue with magnetic resonance imaging (MRI). The T(1) and T(2) relaxivities of CLT1-(Gd-DTPA) were 4.22 and 4.45 mM(-1) s(-1) at 3 T, respectively. The targeted contrast agent specifically bound to tumor tissue and resulted in significant tumor contrast enhancement ...

Journal: :Nature nanotechnology 2008
Adam De la Zerda Cristina Zavaleta Shay Keren Srikant Vaithilingam Sunil Bodapati Zhuang Liu Jelena Levi Bryan R Smith Te-Jen Ma Omer Oralkan Zhen Cheng Xiaoyuan Chen Hongjie Dai Butrus T Khuri-Yakub Sanjiv S Gambhir

Photoacoustic imaging of living subjects offers higher spatial resolution and allows deeper tissues to be imaged compared with most optical imaging techniques. As many diseases do not exhibit a natural photoacoustic contrast, especially in their early stages, it is necessary to administer a photoacoustic contrast agent. A number of contrast agents for photoacoustic imaging have been suggested p...

Journal: :Chemical communications 2015
Michael Harris Sophie Carron Luce Vander Elst Sophie Laurent Robert N Muller Tatjana N Parac-Vogt

Terbium(III) was coordinated to four novel 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) amphiphilic bisamide ligands. The complexes were assembled into mono-disperse micellar nano-aggregates and for the first time Tb(III) has been evaluated as a single lanthanide negative bimodal contrast agent for MRI/OI. The complexes show characteristic Tb(III) emission with quantum yields...

Journal: :Nihon Naika Gakkai Zasshi 2014

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2009
David P Cormode Torjus Skajaa Zahi A Fayad Willem J M Mulder

Nanoparticles have become more and more prevalent in reports of novel contrast agents, especially for molecular imaging, the detection of cellular processes. The advantages of nanoparticles include their potency to generate contrast, the ease of integrating multiple properties, lengthy circulation times, and the possibility to include high payloads. As the chemistry of nanoparticles has improve...

2009
Zahi Fayad David P. Cormode Torjus Skajaa Zahi A. Fayad Willem J.M. Mulder

Nanoparticles have become more and more prevalent in reports of novel contrast agents, especially for molecular imaging, the detection of cellular processes. The advantages of nanoparticles include their potency to generate contrast, the ease of integrating multiple properties, lengthy circulation times, and the possibility to include high payloads. As the chemistry of nanoparticles has improve...

ژورنال: مواد پرانرژی 2016

Glycidyl nitrate is a valuable chemical used for manufacturing poly (glycidyl nitrate) as an energetic polymer. In this study glycidyl nitrate was synthesized by ring opening reaction of epichlorohydrin by nitric acid as nitrating agent in the presence of several different catalysts, and the effect of different catalysts on one pot synthesis of glycidyl nitrate was evaluated. The main purpose o...

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