To meet that challenge, an action plan [2] was designed by the European Respiratory Society (ERS) Thoracic Oncology Assembly officers in March 2010, which was subsequently approved and strongly welcomed by the ERS Executive Committee. Today the Thoracic Oncology Assembly has almost achieved all of the following. 1) To create a Task Force for a European initiative for quality management in lung ...

Targeted cancer therapies offer renewed hope for an eventual 'cure for cancer'. At present, however, their success is often compromised by the emergence of resistant tumor cells. In many cancers, patients initially respond to single therapy treatment but relapse within months. Mathematical models of somatic evolution can predict and explain patterns in the success or failure of anticancer drugs...

objective(s): development of molecules that specifically recognize cancer cells is one of the major areas in cancer research. human epidermal growth factor receptor 2 (her2) is specifically expressed on the surface of breast cancer cells. her2 is associated with an aggressive phenotype and poor prognosis. in this study we aimed to isolate rna aptamers that specifically bind to her2 overexpressi...

Bystander or non-targeted effect is known to be an interesting phenomenon in radiobiology. The genetic consequences of bystander effect on non-irradiated cells have shown that this phenomenon can be considered as one of the most important factors involved in secondary cancer after exposure to ionizing radiation. Every year, millions of people around the world undergo radiotherapy in order to cu...

Cancer is characterized by abnormal cell differentiation in or on the part of body. The most commonly used chemotherapeutic drugs are developed to target rapidly dividing cells, such as cancer but they also damage healthy epithelial cells. This has serious consequences for normal cells and become responsible development various disorders. Several strategies delivering cytotoxic cancerous sites ...

Background: The purpose of this study was to explore the difference in quality indicators for chemotherapy or targeted therapy patients with cancer their last month life.

Molecular targeted therapy as a new means of cancer therapy targeting molecular pathological abnormalities of cancer, the use of target binding ligand and receptor can effectively improve drug lethal to tumor cells while reducing adverse effects on normal tissues and organs, it has been gradually used in clinical treatment. In the treatment of ovarian cancer in comparison with conventional trea...

Objective(s): Development of molecules that specifically recognize cancer cells is one of the major areas in cancer research. Human epidermal growth factor receptor 2 (HER2) is specifically expressed on the surface of breast cancer cells. HER2 is associated with an aggressive phenotype and poor prognosis. In this study we aimed to isolate RNA aptamers that specifically bind to HER2 overexpressi...