In protest of the COVID-19 lockdowns, crowds gathered in downtown Chicago to “Re-Open Illinois” during May 2020. One sign particular, held by a white woman an American flag mask, drew particular attention: “ARBEIT MACHT FREI, JB,” invoking German phrase hung above Nazi concentration camps taunt then governor Illinois, J.B. Pritzker. Reactions this anonymous were swift, but critics missed that J...

The size and shape of tissues are tightly controlled by synchronized processes among cells and tissues to produce an integrated organ. The Hippo signaling pathway controls both cell proliferation and apoptosis by dual signal-transduction states regulated through a repressive kinase cascade. Yap1 and Tead, transcriptional regulators that act downstream of the Hippo signaling kinase cascade, have...

Objective The presence of different missense mutations in sheep breeds have shown that the bone morphogenetic protein receptor 1B (BMPR1B), bone morphogenetic protein 15 (BMP15) and growth differentiation factor 9 (GDF9) genes play a vital role in ovulation rate and prolificacy in ewes. Therefore, the present study investigates BMPR1B, BMP15 and GDF9 genes mutations in prolific ewes of Iranian ...

In a survey of 430 Lori-Bakhtiari sheep at a slaughterhouse in Iran, gallstones were found in the gallbladder of 7 sheep (1.6%). Biliary calculi were more frequent in adult and female sheep (P < 0.05). Chemical analysis of the gallstones revealed 6 sheep with pigment (bilirubin) stones and 1 sheep with cholesterol stones. Chemical composition of bile in these sheep was evaluated. Bacteriologic ...

a study was conducted to investigate the effect of follicular size (small,

78 Ghezel and 76 Mehraban sheep were used to evaluate the effect of fat-tail docking on reproductive performance. Within two days after birth the tails of 32 Ghezel female lambs and 28 Mehraban female lambs were docked using a tight rubber ring. The lambs were allowed to reproduce for three lambing opportunities and their reproductive performances were evaluated. The effect of docking on the fe...

This paper is concerned with the statistical model development issues, necessary for rapid estimation of the rotor sizing for single main rotor helicopters at the preliminary design stage. However, Central Composite Design (CCD) method, simulation-based data collection, linear regression analysis, mathematical modelsdevelopmentand validations through the analysis of variance (ANOVA) were perfor...