Mice which are heterozygous for two complementary lethal t mutations (t6/tw32) exhibit complete male sterility. Experiments have been conducted to determine if spermatozoa from these heterozygous males can fertilize oviducal ova in vitro. The experiments have been designed so that specific barriers which are present during in vivo fertilization can be sequentially removed and the fertilizing ab...

Culture of a mixture of bone marrow cells with and without T6 chromosome marker in diffusion chambers in mice yielded colonies (CFU-DG) containing cells of a single karyotype, suggesting clonality. Injection of individual CFU-DG colonies into lethally irradiated mice resulted in increased spleen colony formation on day 12 (CFU-S). The possibility of endogenous origin was excluded by demonstrati...

Background Belimumab, the first biological drug approved for treatment of patients with Systemic Lupus Erythematosus (SLE), is a fully human IgG1λ monoclonal antibody directed against BlyS (B Lymphocyte Stimulator). BLyS inhibition associated reduction in circulating B subsets and short-lived plasmacells Objectives The aim this study was to characterize cell phenotype SLE at baseline after B-ce...

Present experiment was carried out to check the effect of different concentrations of sucrose (2, 4, 6%), GA 3 (25, 50, 75 ppm) and combination of sucrose and CuSO4 (2% + 200, 4% + 300, 6% + 400 ppm), sucrose and GA 3 (2% + 25 ppm), (4%+50 ppm), (6%+75 ppm) on keeping quality and vase life of carnation cv. ‘Eskimo’. Some postharvest characteristics such as vase life, total soluble solids (TSS),...