The Doxorubicin hydrochloride, popularly known as Adriamycin, is among the most antitumoral drugs used in oncology practice. This is a glycosidic antibiotic from the anthracycline group, which acts directly on the G2/M period, leading to cell death. This study aimed at analyzing placental alteration and congenital malformations in Wistar rats fetuses who were exposed to the chemotherapeutic. Tw...

During healing of a skin wound, cells that are normally dormant must turn on hundreds of genes in order to proliferate, migrate, and repair the defect. The Polycomb family of proteins epigenetically silence target genes and so downregulation of their expression is a potential mechanism for unsilencing repair genes. Quantitative RT-PCR, western blotting, and immunostaining of invitro epithelial ...

BACKGROUND Reports on the cardiorespiratory fitness and body composition of male workers engaged in processing of tea leaves in factories within the tea-estates of West Bengal, under the influence of physiological workload, are quite scanty. OBJECTIVES This cross-sectional study was conducted to evaluate morphometric characteristics based on physiological status and physical fitness of tea fa...

BACKGROUND Wrestling was an important part of the ancient Olympic Games and is still one of the most popular events of the modern Olympic Games. Studies indicate that general physiologic profile of successful wrestlers is high anaerobic power and capacity, muscular strength, above average aerobic power, exceptional flexibility, fat free mass, and a mesomorphic somatotype. OBJECTIVES The objec...