Extensive use of radioimmunoassay for routine measurement of serum thyroid hormones in paediatric thyroid disorders showed inconsistencies between laboratory results based upon adult criteria and clinical observation. To resolve this disparity, serum triiodothyronine (T3) and thyroxine (T4) levels were measured by radioimmunoassay in 354 healthy children aged between 3 weeks and 1 7 years. The ...

Thyroid hormone is an important regulator of energy metabolism and crucial for the development of different tissues, in particular the brain (1, 2). Iodine is an essential trace element for the synthesis of thyroid hormone; as their names indicate, the prohormone T4 contains four iodine atoms, and the principal bioactive hormone T3 contains three iodine atoms. If iodine intake is sufficient, th...

In euthyroid sick syndrome [non-thyroidal illness (NTI)], a number of investigators have described TSH and serum thyroid hormone abnormalities, low T3, low T3 and T4, increased T4, low TSH, etc. Those cases of NTI where there is only T3 decrease [and normal serum T4, free T4 (FT4), and TSH levels] are specifically referred to as low T3 syndrome. However, the information in regard to low T3 synd...

OBJECTIVE: To verify the effect of perinatal asphyxia on thyroid hormone levels in term newborn infants. METHODS: We carried out a case-control study with 17 term and asphyxiated (A) and 17 term and control (N) newborn infants at the Hospital de Clínicas de Porto Alegre. Patients were paired according to color of skin, sex, type of delivery, gestational age, and weight at birth. We collected um...

The goal of this research is to study the effect of benzo-alpha-pyrene (BαP) as a pollutant on the plasma levels of cortisol, thyroxin (T4), and triiodothyronine (T3) hormones, and the T3/T4 ratio in the yellowfin sea bream, Acanthopagrus latus. The BαP (50 mg kg-1) in vegetable oil was peritoneally injected. Blood samples were obtained from the treated and control groups after 3 and 72 hr, res...

The function of the thyroid gland is to synthesize the thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroid cells are the only cells in the body that can absorb the element iodine, which can be found in many foods. These cells combine iodine and the amino acid, tyrosine, to produce T3 and T4. The T3 and T4 hormones are then released into the bloodstream and are transported through...

Purpose Patients with breast cancer (BC) in Area 2 KwaZulu-Natal, South Africa, often present with advanced disease. We performed a review of the patients' sociodemographic characteristics and their reasons for late presentation to identify what changes could be made to improve time to presentation. Patients and Methods Fifty women with T1, T2, T3, or T4 BC were assessed for sociodemographic ...

OBJECTIVE To assess the dentoskeletal changes observed in treatment of Class II, division 1 malocclusion patients with mandibular retrognathism. Treatment was performed with the Herbst orthopedic appliance during 13 months (phase I) and pre-adjusted orthodontic fixed appliance (phase II). METHODS Lateral cephalograms of 17 adolescents were taken in phase I onset (T1) and completion (T2); in t...

Serum thyrotropin (TSH), free thyroxine (T4), and free triiodothyronine (T3) levels illustrate the thyroid function set point, but the interrelations between these have never been characterized in detail. The aim of this study was to examine the associations between TSH and thyroid hormone levels in healthy euthyroid twins and to determine the extent to which the same genes influence more than ...

Objectives – To find the effect Of TSH suppression therapy on levels of TSH, T4 and T3 in hypothyroidism. Methods The study comprised of 40 subjects, classified into 2 groups each, with 20 subjects. Group I – 20 (Healthy individuals) controls aged between 20 – 45 years with euthyroid status. Group II20 Hypothyroid subjects with suppressed levels of TSH aged between 20 to 45 years. The parameter...