INTRODUCTION Data reporting mortality in rheumatic diseases vary widely. The objective of this systematic review and meta-analysis of published data is to provide an accurate overview of the current risk of mortality in rheumatic diseases. METHODS Systematic review and meta-analysis of published studies identified by a sensitive search using free text and MeSH synonyms of "mortality" and of "...

The relative prevalence and clinical pattern of the major rheumatic diseases in the patient population of a teaching hospital in Jamaica were studied over the 3-year period 1974--7. The prevalence of systemic lupus erythematosus approached that of rheumatoid arthritis (RA). All grades of severity of RA were seen, and there was an unusually high proportion of females with RA. Rheumatic fever and...

This article will review how epidemiological studies have advanced our knowledge of both genetic and environmental risk factors for rheumatic diseases over the past decade. The major rheumatic diseases, including rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, systemic lupus erythematosus, scleroderma, osteoarthritis, gout, and fibromyalgia, and...

OBJECTIVE To report the rate and spectrum of the rheumatic manifestations of human immunodeficiency virus (HIV) since the advent of highly active anti-retroviral therapy (HAART). METHODS A retrospective record review of 888 inpatients with HIV for rheumatic manifestations was performed from January 1995 to March 2006. We then searched the 888 records for rheumatic diseases using International...

Introduction Macrophage activation syndrome is a term used to identify hemophagocytic lymphohistiocytosis secondary to rheumatic diseases (rheuHLH). It is a severe, potentially fatal condition that occurs in the context of rheumatic diseases, particularly systemic juvenile idiopathic arthritis. It is part of secondary HLH forms, that are clinically and biochemically similar to primary HLH (pHLH...

Certain rheumatic diseases are associated with unequivocal renal involvement. Examples are the immune complex mediated glomerular nephritis of systemic lupus erythematosus, the renal involvement in other connected tissue disorders such as polyarteritis nodosa, and the renal amyloid that can complicate rheumatoid arthritis or ankylosing spondylitis. Patients with these complications of rheumatic...

OBJECTIVE: To present an updated review concerning the most prevalent diseases with musculoskeletal signs and symptoms that make adolescents seek medical care, giving special emphasis to rheumatic diseases. Our aim is to offer physicians and health care providers the possibility of distinct differential diagnoses, thus allowing them to establish a therapeutic approach and, if necessary, refer t...

Background Many pediatric rheumatic diseases persist into adulthood, with negative squeal from the disease or its treatment. We aimed to assess health related quality of life in a group of children with rheumatic diseases and its relation to disease activity and functional disability.  Materials and Methods Fifty one patients were divided into three groups: Group 1 includes 27 patients diagnose...

Rheumatic disease can loosely be described as any painful condition affecting the loco-motor system, including joints, muscles, connective tissues, and soft tissues around the joints and bones. There is a wide spectrum of rheumatic diseases, many of which involve autoimmunity, including systemic lupus erythematosus and rheumatoid arthritis. A significant body of evidence now links aberrant epig...

Migraine is a very prevalent disease worldwide and major cause of disability. As known for long time, migraine associated with neurogenic inflammation. Epidemiological studies have shown that comorbid several chronic inflammatory diseases, including multiple sclerosis (MS), rheumatic diseases (CIRDs) bowel (IBDs). This brief narrative review highlights some recent data supporting link between t...