Thrombospondin, one of the major glycoproteins released from a-granules of thrombin-stimulated platelets, is a disulfide-linked trimer of 1 60,000-dalton subunits. Cultured human monocytes secreted thrombospondin (determined by an enzyme-linked immunosorbent assay) into the culture medium in a time-dependent manner (1 .45 g/10’ cells/24 hr); secretion was totally blocked by cycloheximide (1 g/m...

Juvenile female Litomosoides sigmodontis secrete a protein (Juv-p120) highly modified with dimethylethanolamine (DMAE). In an attempt to establish the source of this decoration worms were pulsed with [3H]-choline and [3H]-ethanolamine and the radio-isotope labelled products analysed. Both isotope labels were successfully taken up by the worms, as demonstrated by labelling of phospholipids with ...

Mitochondria contain their own genome that is expressed by nuclear-encoded factors imported into the organelle. This review provides a summary of the current state of knowledge regarding the mechanism of protein translation in human mitochondria and the factors involved in this process.

This paper considers the problem of synthesizing a finite-state distributed reactive system. Given a distributed architecture A, identifying several processors 9, . . . , 9, and their interconnection scheme, and a propositional temporal specification 'P, a solution to the synthesis problem consists of finite-state programs II1 , . . . , I I k (one for each processor), whose joint (synchronous) ...