We studied the mechanical variables (the grip force and the total moment of force) and multidigit synergies at two levels (the virtual finger-thumb level, VF-TH, and the individual finger level, IMRL) of a hypothetical control hierarchy during accurate rotation of a hand-held instrumented handle. Synergies were defined as covaried changes in elemental variables (forces and moments of force) tha...

This paper views operating synergies as real options that acquiring companies have in the post-acquisition M&A process. The paper builds on the synergistic restructuring theory, which states that both acquisitions and divestitures are wealth-creating activities. Acquisition synergies are broadly defined as arising both from resource redeployments between the acquirer and the acquisition target ...

UNLABELLED The human brain is believed to simplify the control of the large number of muscles in the body by flexibly combining muscle coordination patterns, termed muscle synergies. However, the neural connectivity allowing the human brain to access and coordinate muscle synergies to accomplish functional tasks remains unknown. Here, we use a surprising pair of synergists in humans, the flexor...

The muscle synergy hypothesis assumes that individual muscle synergies are independent of each other and voluntarily controllable. However, this assumption has not been empirically tested. This study tested if human subjects can voluntarily activate individual muscle synergies extracted by non-negative matrix factorization (NMF), the standard mathematical method for synergy extraction. We defin...

In this contribution we identify the synergies of Operations Research and Data Mining. Synergies can be achieved by integration of optimization techniques into Data Mining and vice versa. In particular, we define three classes of synergies and illustrate each of them by examples. The classification is based on a generic description of aims, preconditions as well as process models of Operations ...

Several recent studies have used matrix factorization algorithms to assess the hypothesis that behaviors might be produced through the combination of a small number of muscle synergies. Although generally agreeing in their basic conclusions, these studies have used a range of different algorithms, making their interpretation and integration difficult. We therefore compared the performance of th...

There is a great potential for mutual beneficial synergies between the two fields of Collaborative Networks and Sustainability science. This potential has in fact been recognized in many fields where these synergies are leading to novel approaches and solutions. It is particularly evident that the challenges of sustainability call for a wide collaboration among multiple stakeholders, as the nee...

Taking inspiration from the hypothesis of muscle synergies, we propose a method to generate open loop controllers for an agent solving point-to-point reaching tasks. The controller output is defined as a linear combination of a small set of predefined actuations, termed synergies. The method can be interpreted from a developmental perspective, since it allows the agent to autonomously synthesiz...

AIM Individuals with cerebral palsy (CP) have impaired movement due to a brain injury near birth. Understanding how neuromuscular control is altered in CP can provide insight into pathological movement. We sought to determine if individuals with CP demonstrate reduced complexity of neuromuscular control during gait compared with unimpaired individuals and if changes in control are related to fu...

The neuromuscular control of human movement can be described by a set of muscle synergies factorized from myoelectric signals. There is some evidence that the selection, activation and flexible combination of these basic activation patterns are of a neural origin. We investigated the muscle synergies during incline and level walking to evaluate changes in the modular organization of neuromuscul...