leukocyte adhesion deficiency type 1 (lad 1) is an autosomal recessive hereditary disorder resulting from deficiency of cd18, characterized by recurrent bacterial infections. we report two consanguineous patients with leukocyte adhesion deficiency type 1( lad1). these two infant boy patients were referred to us, within a short period of time, with the complaints of recurrent infections at the a...

Abstract:Purpose:This study was designed determine the efficacy of bupropion versus placebo in subjects with negative symptoms of schizophrenia.Methods:A convenience sample of 40 patients of both genders aged 18-60 years who were living in psychiatric care centers were randomly treated with bupropion (started with 75 mg twice a day; increased to 100 mg thrice daily) or placebo. The diagnosis of...

Background: The nature of the premenstrual condition is based upon premenstrual symptoms, which women experience them and only in those cases where symptoms have negative influence on the physical, psychological or social functioning; we speak of a premenstrual syndrome, which reduce quality of life. The objective of this study is to assess frequency and severity of PMS in Medical Science Unive...

background and aims: blacks have a higher rate of chronic medical conditions (cmc), disability, and depressive symptoms compared to whites. the present study compared blacks and whites for bidirectional associations between cmc, disability, and depressive symptoms over a 25-year period. methods: data came from all five waves (1986, 1989, 1994, 2001, and 2011) of the americans’ changing lives st...

psychological symptoms are considered as one of the aspects and consequences of cardiovascular diseases (cvds), management of which can precipitate and facilitate the process of recovery. evaluation of the psychological symptoms can increase awareness of treatment team regarding patients’ mental health, which can be beneficial for designing treatment programs (1). however, time-consuming proces...

conclusions overall, coq10 was determined to have positive effects on liver injury and its related behavioral and biochemical changes. results the serum levels of alanine-aminotransferase (alt), aspartate-aminotransferase (ast), and nh4 show significant increases (p < 0.05). the groups treated with coq10 were shown to have significantly lower clinical grade of encephalopathy (p = 0.001), higher...

wegener's granulomatosis is an uncommon inflammatory disease that manifests as vasculitis, granulomatosis, and necrosis. it usually involves the upper and lower respiratory tracts and kidneys. although it may essentially involve any organ, gastrointestinal (gi) involvement is notably uncommon. a 20-year-old male patient presented with epigastric pain, vomiting, hematemesis, and melena. on physi...

the aim of this study was assessing the effectiveness of child-centered play therapy (ccpt) on reducing internalizing symptoms in children and reduced parental stress in mothers. the method of this study was quasi-experimental research study using a pretest-post-test along with the control group. a group of 20 children with 7 and 8 age in 2012-2013 school year (n=10 experimental and n=10 contro...