نتایج جستجو برای: sympathetic nerves

تعداد نتایج: 55045  

Journal: :The American journal of physiology 1998
Hiroshi Miyano Yasunori Nakayama Toshiaki Shishido Masashi Inagaki Toru Kawada Takayuki Sato Hiroshi Miyashita Masaru Sugimachi Joe Alexander Kenji Sunagawa

We investigated the dynamic sympathetic regulation of left ventricular end-systolic elastance ( E es) using an isolated canine ventricular preparation with functioning sympathetic nerves intact. We estimated the transfer function from both stellate ganglion stimulation to E es and ganglion stimulation to heart rate (HR) for both left and right ganglia by means of the white noise approach and tr...

2014
Eleana Manousiouthakis Monica Mendez Madeline C. Garner Prisca Exertier Takako Makita

The mechanisms responsible for establishing correct target innervation during organ development are largely unknown. Sympathetic nerves follow blood vessels--typically arteries--to reach their endorgans, suggesting the existence of vascular guidance cues that direct axonal extension. The sinoatrial node and the ventricle of the heart receive sympathetic innervation from the stellate ganglia (ST...

Journal: :Neuron 2001
Markus Glatzel Frank L. Heppner Kathryn M. Albers Adriano Aguzzi

Transmissible spongiform encephalopathies are commonly propagated by extracerebral inoculation of the infectious agent. Indirect evidence suggests that entry into the central nervous system occurs via the peripheral nervous system. Here we have investigated the role of the sympathetic nervous system in prion neuroinvasion. Following intraperitoneal prion inoculation, chemical or immunological s...

Journal: :American journal of physiology. Gastrointestinal and liver physiology 2010
C A Cobine G W Hennig Y R Bayguinov W J Hatton S M Ward K D Keef

The morphology of interstitial cells of Cajal (ICC) in the circular muscle layer of the cynomolgus monkey internal anal sphincter (IAS) and rectum and their relationship to sympathetic and nitrergic nerves were compared by dual-labeling immunohistochemistry. Contractile studies confirmed that nitrergic nerves participate in neural inhibition in both regions whereas sympathetic nerves serve as e...

Journal: :American journal of physiology. Heart and circulatory physiology 2013
Liang-Wu Fu John C Longhurst

Thinly myelinated Aδ-fiber and unmyelinated C-fiber cardiac sympathetic (spinal) sensory nerve fibers are activated during myocardial ischemia to transmit the sensation of angina pectoris. Although recent observations showed that myocardial ischemia increases the concentrations of opioid peptides and that the stimulation of peripheral opioid receptors inhibits chemically induced visceral and so...

Journal: :Physiological research 2009
T Ikeda H Hirakawa T Kemuriyama Y Nishida T Kazama

Stellate ganglion blockade (SGB) with a local anesthetic increases muscle sympathetic nerve activity in the tibial nerve in humans. However, whether this sympathetic excitation in the tibial nerve is due to a sympathetic blockade in the neck itself, or due to infiltration of a local anesthetic to adjacent nerves including the vagus nerve remains unknown. To rule out one mechanism, we examined t...

2015
Heung Yong Jin Hong Sun Baek Tae Sun Park

Diabetic neuropathy is one of the major complications of diabetes, and it increases morbidity and mortality in patients with both type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM). Because the autonomic nervous system, for example, parasympathetic axons, has a diffuse and wide distribution, we do not know the morphological changes that occur in autonomic neural control and the...

Journal: :Circulation research 2016
Luc Pardanaud Laurence Pibouin-Fragner Alexandre Dubrac Thomas Mathivet Isabel English Isabelle Brunet Michael Simons Anne Eichmann

RATIONALE Arterial endothelial cells are morphologically, functionally, and molecularly distinct from those found in veins and lymphatic vessels. How arterial fate is acquired during development and maintained in adult vessels is incompletely understood. OBJECTIVE We set out to identify factors that promote arterial endothelial cell fate in vivo. METHODS AND RESULTS We developed a functiona...

Journal: :Hypertension 1983
Y Furukawa P Scipione M N Levy

In anesthetized dogs with the left cardiac sympathetic nerves and both vagal nerves intact, angiotensin II (AII) induced a substantial, dose-dependent increase in arterial blood pressure and small increments in cardiac cycle length and ventricular contractile force. In dogs in which the cardiac sympathetic and vagal nerves had been interrupted, AII produced similar increases in blood pressure a...

Journal: :Circulation. Cardiovascular interventions 2017
Nicholas Jackson Sigfús Gizurarson Mohammed Ali Azam Benjamin King Andrew Ramadeen Nima Zamiri Andreu Porta-Sánchez Abdul Al-Hesayen John Graham Marjan Kusha Stéphane Massé Patrick F H Lai John Parker Rohan John Tim-Rasmus Kiehl Govind Krishna Kumar Nair Paul Dorian Kumaraswamy Nanthakumar

BACKGROUND The therapeutic potential of renal denervation (RDN) for arrhythmias has not been fully explored. Detailed mechanistic evaluation is in order. The objective of the present study was to determine the antiarrhythmic potential of RDN in a postinfarct animal model and to determine whether any benefits relate to RDN-induced reduction of sympathetic effectors on the myocardium. METHODS A...

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