The early studies of Redaelli (1924) and Benham (1931) have shown that the rabbit is readily susceptible to infection produced by the intravenous inoculation of Candida albicans. The mouse was considered to be resistant to disease by this yeast. This concept was apparently based upon the fact that mice are resistant to infection following intraabdominal injection; however, rabbits also are resi...

The early studies of Redaelli (1924) and Benham (1931) have shown that the rabbit is readily susceptible to infection produced by the intravenous inoculation of Candida albicans. The mouse was considered to be resistant to disease by this yeast. This concept was apparently based upon the fact that mice are resistant to infection following intraabdominal injection; however, rabbits also are resi...

objective(s):cone snails are estimated to consist of up to 700 species. the venom of these snails has yielded a rich source of novel peptides. this study was aimed to study the analgesic effect of persian gulf conus textile and its comparison with morphine in mouse model. materials and methods: samples were collected in larak island. the venom ducts were isolated and kept on ice then homogenize...

The aim of the present study was to evaluate Vitamin C (VC) as a potent natural antioxidant to mitigate the genotoxic effects of Arsenic trioxide and sodium fluoride in Swiss albino mice in vivo. The study was divided into eight groups consisting of control treated with normal saline (Group I), Group II, III, IV, V, VI, VII and the VC group with only Vitamin C (500 mg/kgbw). Arsenic trioxide (4...

To evaluate the chemopreventive potential of quercetin in an experimental skin carcinogenesis mouse model. Skin tumor was induced by topical application of 7, 12-dimethyl Benz (a) anthracene (DMBA) and Croton oil in Swiss albino mouse. Quercetin was orally administered at a concentration of 200 mg/kg and 400 mg/kg body weight daily for 16 weeks in mouse to evaluate chemopreventive potential. Sk...

An unexpected high level of acute lethality has been documented following Photofrin II-mediated photodynamic therapy (PDT) treatments which were localized to the hind leg of normal and tumor-bearing mice. Doses of PDT which induced lethality (10 mg/kg Photofrin II, 200-500 J/cm2) were in the range of doses required to obtain murine tumor cures. The percentage of lethality was proportional to th...