Membrane ruffling induced by growth factor stimulation is caused by actin remodeling, which is mediated by various signaling molecules including Rac. We have shown that SWAP-70, which binds phosphatidylinositol trisphosphate, is one such molecule required for membrane ruffling in mouse kidney cells. Here, we show that SWAP-70 directly binds to F-actin. The bacterially expressed C-terminal regio...

In this paper we extend the class of energy functions for which the optimal α-expansion and αβ-swap moves can be computed in polynomial time. Specifically, we introduce a class of higher order clique potentials and show that the expansion and swap moves for any energy function composed of these potentials can be found by minimizing a submodular function. We also show that for a subset of these ...

This paper estimates the price for restructuring risk in the U.S. corporate bond market during 1999-2005. Comparing quotes from default swap (CDS) contracts with a restructuring event and without, we find that the average premium for restructuring risk represents 6% to 8% of the swap rate without restructuring. We show that the restructuring premium depends on firmspecific balance-sheet and mac...

The pattern matching problem with swaps is to find all occurrences of a pattern in a text while allowing the pattern to swap adjacent symbols. The goal is to design fast matching algorithm that takes advantage of the bit parallelism of bitwise machine instructions. We point out a fatal flaw in the algorithm proposed by Ahmed et al. [The swap matching problem revisited, Theor. Comp. Sci. 2014], ...

It is widely recognised that delta-hedged positions in options can be used to trade volatility. To facilitate volatility trading for their clients, several institutions routinely offer variance swaps. A variance swap is a financial contract that upon expiry pays the difference between a standard historical estimate of daily return variance and a fixed rate determined at inception. As in any swa...

PURPOSE To quantify factors affecting test-retest variability of threshold measurements over a series of 3 serial visual fields (VF). DESIGN Prospective comparative observational study. PARTICIPANTS Forty-one normals, 10 suspects and 35 stable glaucoma patients. METHODS All subjects performed 3 standard and 3 short-wavelength automated perimetry (SWAP) VFs. At each VF location, severity (...

A swap instruction, which exchanges a value in memory with a value of a register, is available on many architectures. The primary application of a swap instruction has been for process synchronization. In this paper we show that a swap instruction can often be used to coalesce loads and stores in a variety of applications. We describe the analysis necessary to detect opportunities to exploit a ...

Intradermal vaccination of mice with soluble adult worm antigen (SWAP) in combination with Mycobacterium bovis BCG (Swedish strain) induced significant protection against subsequent infection with Schistosoma mansoni cercariae. When cholera toxin (CT) was used as an adjuvant in combination with SWAP or fraction A, no significant protection was observed. However, intradermal vaccination in combi...