‘Comfort care techniques’ reduce pain and anxiety associated with screening for ROP? A randomised controlled trial in 40 infants (O’Sullivan, 2010) used swaddling in the control group (n=20), who also received 0.2 ml of sterile water given by mouth using a syringe and a soother. The intervention group (n=20) were also swaddled, and received 0.2 ml of sucrose 24% given by mouth using a syringe a...

INTRODUCTION Ultrasound represents a method of examination of hips of newborn babies capable of defining hip condition and distinguishing stable and unstable hips based on morphological elements. It is accepted in a large number of countries as a method of examination of high risk newborns, or as a method of systematic screening. OBJECTIVE The objective of this study was to investigate correl...

BACKGROUND Developmental dysplasia of the hip (DDH) always leads to cartilage degeneration and osteoarthritis of the hip joint. However, the diagnosis of early cartilage degeneration in DDH is still a clinical challenge. This study aims to investigate the dynamic changes of bone and cartilage in the hip of a rat model of DDH and to explore the potential application of microcomputed tomography (...

“Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage. Each individual learns the application of the word through experiences related to injury in early life”[1]. It is now clear that premature and full-term newborns have the neuroanatomical pathways from the periphery to cortex required for nociception. I...

says little that Eyler did not later include in his excellent intellectual biography of Farr, Victorian social medicine (1980). Several of the other essays also review ground substantially covered elsewhere in print. Each paper is accompanied by a discussion that the organizers of the conference self-consciously designed to further the exchange of professional perspectives by having an epidemio...

place them under one roof (as in Celle, though it is true they were divided from each other). He also tells how, in Saxony, it was seriously suggested in the early eighteenth century that lunatics should be shipped to the Venetian galleys or alternatively to British and Dutch colonies; and how either sheer fear of the insane, or a plain inability to cope with them, prevented the Mayor of Frankf...

We examine the treatment of urinary incontinence in Ancient Egypt with faïence in the light of current concerns regarding the treatment of dysfunctional elimination in children with milk of magnesia. The origins of medical science in Africa and their influence on Western medicine are attested to by surviving documents from the XVIII Dynasty of the New Kingdom period of Pharaonic Egypt. One such...

Febrile seizure risk 7 to 10 days after measles-mumps-rubella-varicella (MMRV) is double that of separate measles-mumps-rubella (MMR) and varicella vaccines among 1-year-olds. Whether MMRV or MMR and varicella affect febrile seizure risk among 4-to 6-year-olds has not been reported. Using Vaccine Safety Datalink data, we examined risk for febrile seizures after measles-containing vaccines. This...

Nanoparticles engineered for biomedical applications are meant to be in contact with protein-rich physiological fluids. These proteins are usually adsorbed onto the nanoparticle's surface, forming a swaddling layer that has been described as a 'protein corona', the nature of which is expected to influence not only the physicochemical properties of the particles but also the internalization into...

Recent scientific studies have added more and more consistent evidence that the newborn, even if preterm, is very sensitive to the nociceptive stimulus. The baby responds with a well known physiological, metabolic and hormonal reaction, that, if repeated, may lead to short and medium term negative effects on the newborn. This vulnerability to painful stimulus, especially in preterm infants, can...