BACKGROUND Tissue damage caused by surgical procedures nearly always results in pain. The effective management of postoperative pain remains a challenge because of its influence on the surgical outcome and its critical role in early mobilization and functionality. Recent research on postoperative pain management supports a treatment approach known as "multimodal analgesia," which comprises the ...

BACKGROUND One of the most important problems after episiotomy is perineal pain which is more severe on the first day of postpartum period. The aim of this study was to compare the analgesic effects of indomethacin suppository and lidocaine cream in the management of post-episiotomy pain. MATERIALS AND METHODS In a randomized, controlled trial, 60 primiparous women who had mediolateral episio...

37 febrile children aged between 3 months and 6 years were treated with paracetamol in a dose of 15--20 mg/kg by either oral elixir or rectal suppository. The rectal route was found to have an equal antipyretic effect and offers a practical alternative in those children for whom the oral route is not possible.20

Let Tt = e−tL be a semigroup of self-adjoint linear operators acting on L(X,μ), where (X, d, μ) is a space of homogeneous type. We assume that Tt has an integral kernel Tt(x, y) which satisfies the upper and lower Gaussian bounds: C1 μ(B(x, √ t)) exp ( −c1d(x, y)/t ) ≤ Tt(x, y) ≤ C2 μ(B(x, √ t)) exp ( −c2d(x, y)/t ) . By definition, f belongs to H L if ‖f‖H1 L = ‖ supt>0 |Ttf(x)|‖L1(X,μ) < ∞. W...

objective : the study evaluated the efficacy and safety of vaginal rogesterone on prevention of recurrent preterm labor. materials and methods: total number of 70 patients with preterm labor treated with intravenous magnesium sulfate in perinatology department of valiasr hospital entered to a randomized clinical trial. treatment group after inhibition of preterm labor with magnesium sulfate rec...

BACKGROUND A new formulation of olanzapine available for terminally ill patients is needed. Rectal administration using suppositories is an alternative for patients for whom administration via the oral route is not feasible. In the present study, we prepared olanzapine suppositories, and confirmed using pharmaceutical tests. Furthermore, we demonstrated the efficacy and safety of olanzapine sup...

Colitis occurs with exposure to various chemicals, including alcohol, radiocontrast agents, glutaraldehyde, formalin, ergotamine, hydrogen peroxide and drugs (1). Frequency of colitis induced by drugs is often under estimated. Antibiotics, 5-fluorouracil (5-FU), hydroxycarbamide, nonsteroidal anti-inflammatory drugs (NSAIDS) and aspirin are usually incriminated (2-4). We report the case of seve...

Let JL be a positive Borel measure with support supp JL = E C -1,1) and let