Background: Repetitive Transcranial Magnetic stimulation (rTMS) is commonly targeted at the dorsolateral prefrontal cortex (dlPFC) for treatment-resistant depression (TRD). For nonresponders, providers may augment treatment with alternative targets. Sagittal midline targets including dorsomedial (dmPFC), and supplementary motor area (SMA) are preeminent obsessive compulsive disorder (OCD) also ...

BACKGROUND Congenital central hypoventilation syndrome (CCHS) is a rare neuro-respiratory disorder associated with mutations of the PHOX2B gene. Patients with this disease experience severe hypoventilation during sleep and are consequently ventilator-dependent. However, they breathe almost normally while awake, indicating the existence of cortical mechanisms compensating for the deficient brain...