نتایج جستجو برای: sulfonamides

تعداد نتایج: 2874  

2012
Mariska Muijsers An Martel Pascale Van Rooij Kris Baert Griet Vercauteren Richard Ducatelle Patrick De Backer Francis Vercammen Freddy Haesebrouck Frank Pasmans

BACKGROUND The establishment of safe and effective protocols to treat chytridiomycosis in amphibians is urgently required. In this study, the usefulness of antibacterial agents to clear chytridiomycosis from infected amphibians was evaluated. RESULTS Florfenicol, sulfamethoxazole, sulfadiazine and the combination of trimethoprim and sulfonamides were active in vitro against cultures of five B...

Journal: :The Journal of biological chemistry 1945
M R STETTEN C L FOX

When Escherichia coli was grown in a synthetic medium containing salts, amino acids, and glucose in the presence of bacteriostatic concentrations of sulfonamides, an increase in total diasotizable amine was noted (1). This has nolv been found to be due to the production of a new heterocyclic amine, the nature of mhich may ultimately throIv light on the mechanism of sulfonamide bacteriost,asis. ...

Journal: :Bioorganic & medicinal chemistry letters 2007
Michael F Parker Joanne J Bronson Donna M Barten Jason A Corsa Wengsheng Du Kevin M Felsenstein Valerie L Guss Darcy Izzarelli Alice Loo Kate E McElhone Larry R Marcin Ramesh Padmanabha Roger Pak Craig T Polson Jeremy H Toyn Sam Varma Jian Wang Victoria Wong Ming Zheng Susan B Roberts

A series of amino-caprolactam sulfonamides were developed from a screening hit. Compounds with good in vitro and in vivo gamma-secretase activity are reported.

Journal: :Chemical communications 2009
Patrick Loos Matthias Riedrich Hans-Dieter Arndt

2-Imidazolines and imidazoles have been accessed by an aza-Wittig sequence featuring novel N-acylation methodology for sulfonamides and optimized conditions for ring closure.

Journal: :Chemical communications 2011
Chang-Bin Yu Kao Gao Duo-Sheng Wang Lei Shi Yong-Gui Zhou

Asymmetric hydrogenation of cyclic enesulfonamides affords chiral cyclic sulfonamides using Pd(OCOCF(3))(2)/diphosphine complexes as catalysts with up to 98% ee.

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