Bovine aortic endothelial cells were cultured in medium containing [3H]glucosamine and concentrations of [“S]sulfate ranging from 0.01 to 0.31 mM. While the amount of [‘H]hexosamine incorporated into chondroitin sulfate and heparan sulfate was constant, decreasing concentrations of sulfate resulted in lower [‘“SIsulfate incorporation. Sulfate concentrations greater than 0.1 1 mM were required ...

Serum/blood (S/B) concentration ratios for ethyl glucuronide (EtG) and ethyl sulfate (EtS) are missing from the literature, and the aim of this study was to determine these ratios in samples from patients at admission to an alcohol rehabilitation clinic. Two blood samples were collected simultaneously, and EtG and EtS were analyzed in whole blood and serum, respectively, using a liquid chromato...

Anthropogenic aerosols are hypothesized to decrease cloud drop radius and increase cloud droplet number concentration enhancing cloud optical depth and albedo. Here results have been used from a chemical transport model driven by the output of a numerical weather prediction model to identify an incursion of sulfate-laden air from the European continent over the mid–North Atlantic under the infl...

In this study, 33 different polysaccharides were prepared to investigate the structure-activity relationships between the polysaccharides, mainly from marine algae, and anti-complement activity in the classical pathway. Factors considered included extraction methods, fractionations, molecular weight, molar ratio of galactose to fucose, sulfate, uronic acid (UA) content, linkage, branching, and ...

a b s t r a c t   zinc deficiency in man is characterized by skin lesion, alopecia and has been linked to growth retardation and mental disturbance. for supplementation purposes zinc is currently presented as its sulfate salt, from which uptake by the body is poor, necesseting the administration of high doses. this leads to a range of unpleasant side effects. in order to increase the bioavailab...

A novel invertebrate gastrointestinal transport mechanism has been shown to couple chloride/sulfate exchange in an electrogenic fashion. In the lobster, Homarus americanus, the hepatopancreas, or digestive gland, exists as an outpocketing of the digestive tract, representing a single cell layer separating the gut lumen and an open circulatory system comprised of hemolymph. Investigations utiliz...

In this work, the dissolution-absorption studies were conducted on marketed tablets of acyclovir (ACIVIR-200mg) and the mucoadhesive tablets of acyclovir using varying concentration of sodium lauryl sulfate as a permeation enhancer. The purpose of this study was to improve the absorption of acyclovir using sodium lauryl sulfate as permeation enhancer. The everted and perfused intestine model wa...

In osteoarthritis the articular cartilage becomes roughened, fibrillar, softened, thinned, and finally eroded, with secondary changes occurring in the underlying bone. Histologically, early cartilage lesions in osteoarthritis are characterized by loss of metachromasia in the matrix, and it has been postulated that the initial disturbance involves the intercellular substance (1, 2). The decrease...