Although quinolone resistance results mostly from chromosomal mutations in Enterobacteriaceae, it may also be mediated by plasmid-encoded Qnr determinants. Qnr proteins protect DNA from quinolone binding and compromise the efficacy of quinolones such as nalidixic acid. Qnr proteins (QnrA-like, QnrB and QnrS) have been identified worldwide with a quite high prevalence among Asian isolates with a...

OBJECTIVES The aim of this study was to determine the prevalence and characteristics of qnr-carrying Salmonella isolates from humans in southern Taiwan. METHODS A total of 446 Salmonella isolates collected between 2003 and 2006 were screened for qnrA, qnrB and qnrS by PCR experiments. Genetic structures of qnr were determined by PCR-based methods or direct sequencing of plasmid DNA. RESULTS...

Using a rapid screening method, we investigated the prevalence of fecal carriage of antimicrobial drug-resistant Escherichia coli in 3,174 healthy children from 4 urban settings in Peru and Bolivia. High resistance rates were observed for ampicillin (95%), trimethoprim-sulfamethoxazole (94%), tetracycline (93%), streptomycin (82%), and chloramphenicol (70%). Lower resistance rates were observed...

The genome of a multidrug-resistant Salmonella Agona isolated from Larus audouinii (Audouin's gull) in Spain was examined. The isolate showed high levels of resistance to different antimicrobials, including third generation cephalosporins and fluoroquinolones, which is a public health concern as those being used to treat severe salmonellosis in humans. Whole genome sequencing revealed the strai...

Genetic Evaluation, Familial Screening and Exercise Ricardo Stein,1,2,3,4 Juan Pablo Trujillo,5,6 Anderson Donelli da Silveira,1,4 Arsonval Lamounier Júnior,5,6 Lorenzo Monserrat Iglesias5,6 Programa de Pós-Graduação em Cardiologia e Ciências Cardiovasculares da Faculdade de Medicina da Universidade Federal do Rio Grande do Sul1; Grupo de Pesquisa em Cardiologia do Exercício do Hospital de Clín...

A total of 126 Salmonella spp. isolates from pigs belonging to 13 serotypes (Typhimurium, Derby, Infantis, Enteritidis, Agona, Kaapstad, London, Montevideo, Bredeney, Give, Oritamerin, Schwarzengrund and Tennessee) were tested for sensitivity to 14 antibiotics. Resistance to 1–8 antibiotics was demonstrated in 64 isolates (59.8%), classified into seven serotypes with the most frequent being Sal...

Fifty-five Aeromonas hydrophila isolates, which were colected from infected tilapia Oreochromis niloticus at aquaculture farms in Thailand, were tested for their antimicrobial susceptibilities against 11 drugs including ampicilin (ABPC), kanamycin (KM), streptomycin (SM), chloramphenicol (CP), florfenicol (FF), tetracycline (TC), sulfamonomethoxine (SMMX), trimethoprim (TMP) and three quinolone...

The presence and genetic content of integrons was investigated in eight Salmonella enterica Typhimurium DT104 isolates from different pig herds in Denmark. Two different integrons were identified using PCR and sequencing. Each of the integrons carried a single resistance cassette in addition to the sul1 and qacE delta 1 genes characteristic of integrons. The first integron encoded the ant (3")-...

Corrêa A.M.R., Zlotowski P., Rozza D.B., Borba M.R., Leal J.S., Cruz C.E.F. & Driemeier D. 2006. Postweaning multisystemic wasting syndrome in farmed wild boars (Sus scrofa) in Rio Grande do Sul. Pesquisa Veterinária Brasileira 26(3):154-156. Department of Veterinary Pathology, Faculty of Veterinary Medicine, Federal University of Rio Grande do Sul (UFRGS), Av. Bento Gonçalves 9090, Porto Alegr...