نتایج جستجو برای: subthalamic nucleus
تعداد نتایج: 112660 فیلتر نتایج به سال:
OBJECTIVE To present the result and experience of subthalamic nucleus deep brain stimulation for Parkinson's disease. DESIGN Case series. SETTING Prince of Wales Hospital, Hong Kong. PATIENTS A cohort of patients with Parkinson's disease received subthalamic nucleus deep brain stimulation from September 1998 to January 2010. Patient assessment data before and after the operation were coll...
The subthalamic nucleus (STN) is a small but vitally important structure in the basal ganglia. Because of its small volume, and its localization in the basal ganglia, the STN can best be visualized using ultra-high resolution 7 Tesla (T) magnetic resonance imaging (MRI). In the present study, first we individually segmented 7 T MRI STN masks to generate atlas probability maps. Secondly, the ind...
During the "DBS Canada Day" symposium held in Toronto July 4-5, 2014, the scientific committee invited experts to discuss three main questions on target selection for deep brain stimulation (DBS) of patients with Parkinson's disease (PD). First, is the subthalamic nucleus (STN) or the globus pallidus internus (GPi) the ideal target? In summary, both targets are equally effective in improving th...
The recent announcement that a Lasker award has been attributed to Professor Alim-Louis Benabid for pioneering the application of high frequency stimulation, named deep brain stimulation, of the subthalamic nucleus in patients suffering from Parkinson's disease prompts us to evoke the decisive role played by the non-human primate model in the discovery of this neurosurgical therapy, now regarde...
Parkinson's disease (PD) is the most prevalent hypokinetic movement disorder, and symptomatic PD pathogenesis has been ascribed to imbalances between the direct and indirect pathways in the basal ganglia circuitry. Here, we applied glutamate receptor blockers to the subthalamic nucleus (STN) of parkinsonian rats and evaluated locomotor behaviors via single-unit and local-field recordings. Using...
Introduction: Psychiatric side effects of deep brain stimulation are not uncommon. It is often limited to transient mood alterations. We report for the first time a case of acute stimulationdependent fear during intraoperative test stimulation. Case presentation: During test stimulation for electrode placement to the left subthalamic nucleus, a 58-year-old caucasian man with Parkinson’s disease...
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