BACKGROUND Subclinical thyroid dysfunction has been implicated as a risk factor for cognitive decline in old age, but results are inconsistent. We investigated the association between subclinical thyroid dysfunction and cognitive decline in the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER). METHODS Prospective longitudinal study of men and women aged 70-82 years with pre-e...

OBJECTIVES To examine the risk of atrial fibrillation in relation to the whole spectrum of thyroid function in a large cohort of patients. DESIGN Population based cohort study of general practice patients identified by linkage of nationwide registries at the individual level. SETTING Primary care patients in the city of Copenhagen. SUBJECTS Registry data for 586,460 adults who had their t...

AIMS Altered thyroid hormone metabolism characterized by a low triiodothyronine (T3), so-called low-T3 syndrome, is a common finding in patients with severe systemic diseases. Additionally, subclinical thyroid dysfunction, defined as abnormal thyroid stimulating hormone (TSH) and normal thyroxine (T4), causes left ventricular dysfunction. Our objective was to identify the prevalence and prognos...

The thyroid disorders are found to be prevalent in Himalayan and sub Himalayan regions and the studies focusing on the association between thyroid function markers and lipid metabolism are sparse. The present study was aimed to study the impact of thyroid hyperfunction on lipoprotein metabolism and hepatic lipase activity. Two ninety subjects (255 females, 35 males) aged 2555 years with a clini...

Subclinical hyperthyroidism is defined as low or undetectable serum thyrotropin concentration in the presence of levels of free thriiodothyronine and thyroxine within the reference range. Despite the conflicting results from many observational studies, this thyroid disorder has been associated with an increased risk of developing atrial fibrillation, left ventricular hypertrophy, increased hear...

Background: Hypothyroidism is one of the most common endocrinal disorders which are mainly diagnosed basing on laboratory investigations. In hypothyroidism, patients present with non-specific symptoms. Depression non specific symptoms hypothyroidism. Grading and management depression along hypothyroidism essential to prevent risk harm provide potential benefit patient. Method: A 35 year old wom...

Thyroid hormone production, metabolism, and action change with aging. The reference ranges for serum thyrotropin and thyroid hormones are derived mainly from younger populations. Thus, the prevalence of subclinical thyroid dysfunction is increased greatly in the elderly. However, it is unclear whether mild thyroid dysfunction in the elderly is associated with adverse outcomes. In this review, w...

Subclinical hyperthyroidism and subclinical hypothyroidism are characterized by abnormal thyroid stimulating hormone (TSH) with normal free thyroxine. Subclinical thyroid diseases, to date, have received less attention compared with other thyroid diseases since they are asymptomatic. This study aimed to verify the association between subclinical thyroid diseases and cardiovascular diseases (CVD...

OBJECTIVE Post-treatment endocrine disturbances are common in cancer patients who have received radiotherapy or chemotherapy. The objective of this study was to evaluate the thyroid functions of long-term survivors of pediatric Hodgkin's lymphoma treated with chemotherapy and radiotherapy. METHODS Thyroid functions of 55 Hodgkin's lymphoma patients (M/F:2.05/1) in complete remission were eval...

Thyroid disease commonly affects women of childbearing age and is the second most common endocrinological disorder diagnosed in pregnancy after gestational diabetes. In normal gestation, the thyroid gland adapts its structure and function to satisfy increasing functional demand. The marked physiological changes that occur during normal pregnancy make it necessary to use specific reference range...