at present, when a clinical diagnosis of parkinson’s disease (pd) is made, serious damage has already been done to nerve cells of the substantia nigra pars compacta. the diagnosis of pd in its earlier stages, before this irreversible damage, would be of enormous benefit for future treatment strategies designed to slow or halt the progression of this disease that possibly prevents accumulation o...

Damage assessment is one of the crucial topics in the operation of structures. Multiplicities of structural elements and joints are the main challenges about damage assessment of space structure. Vibration-based damage evaluation seems to be effective and useful for application in industrial conditions and the low-cost. A method is presented to detect and assess structural damages from changes ...

A comparative assessment of several vibration based statistical time series methods for Structural Health Monitoring (SHM) is presented via their application to a scale aircraft skeleton laboratory structure. A brief overview of the methods, which are either scalar or vector type, non–parametric or parametric, and pertain to either the response–only or excitation–response cases, is provided. Da...

Kidney damage is defined as structural or functional abnormalities of the kidney with or without decreased glomerular filtration rate (GFR), manifest by either pathological abnormalities or abnormalities in blood or urine tests or imaging studies 1,2 . The term chronic kidney disease (CKD) refers to patients with kidney damage or a GFR less than 60ml/min/1.73m 2 with or without kidney damage fo...

Imaging single proteins has been a long-standing ambition for advancing various fields in natural science, as for instance structural biology, biophysics, and molecular nanotechnology. In particular, revealing the distinct conformations of an individual protein is of utmost importance. Here, we show the imaging of individual proteins and protein complexes by low-energy electron holography. Samp...

Tehran is one of the densely populated metropolises located in earthquake-prone regions. Tehran, the population of which surpasses 8 million people, is the most populated area in Iran. There are historical evidences confirming that catastrophic earthquakes have destroyed the city in past years. In the present paper, our study covers all parts of Tehran because there is the potential of signific...

A Conceptual Framework upon which the study of disasters can be organized is essential for understanding the epidemiology of disasters, as well as the interventions/responses undertaken. Application of the structure provided by the Conceptual Framework should facilitate the development of the science of Disaster Health. This Framework is based on deconstructions of the commonly used Disaster Ma...

Damage localization and quantification constitute different aspects of structural damage diagnosis, which are particular interest in the Structural Health Monitoring field. Therein, a classical solution is model updating, where parameters finite element possibly damaged structure optimized to match with corresponding estimated from its vibration responses. To avoid ill-posedness updating proble...

Early diagnosis of rheumatoid arthritis (RA) combined with early initiation of an appropriate treatment regimen is acknowledged as an important factor in improving clinical outcomes in patients with RA. Early diagnosis allows treatment intervention to occur sooner in order to inhibit the progression of structural joint damage as well as providing improved patient quality of life. Unfortunately,...