نتایج جستجو برای: structural and functional alteration
تعداد نتایج: 16955770 فیلتر نتایج به سال:
the effect of the presence of perforations on he stresses of a plate is a problem which is of great interest in structural design and in the mathemattical theory of elasticity. among the many hole patterns that are likely to require consideration is the ring of equally spaced circular holes. the present worke investigates stress & strain analysis of a thin isotropic circular plate containing a ...
Introduction: Mutations in the BRCA1 gene are major risk factors for breast and ovarian cancers. However, the relationship between some BRCA1 mutations and cancer risk remains largely unknown. Cancer risk predictions could be improved by evaluation of the impairment degree in the BRCA1 functions due to a specific mutation. This study aimed to assess the functional effect of a novel variant (Glu...
Background & Aims: Increase of blood glucose levels leads to structural and functional changes in reproductive system. This investigation was conducted to evaluate the effects of diabetes on the structure and function of testicular tissue focusing on the ultrastructure of the epithelium of seminiferous tubules. Materials & Methods: Diabetes was induced in adult male rats by single intraperiton...
A new approach for investigating the mechanisms and evolution of cardiac muscle cell injury was presented by applying fine structural extracellular protein tracers in the catecholamine-induced cardiac muscle cell injury model. The results with these diffusion tracers indicated striking functional changes at the level of coronary microcirculation followed by early permeability alteration of card...
Objective: Rheumatoid arthritis is a chronic inflammatory disease which causes structural and functional changes in foot joints and results in alteration of plantar pressures. Therefore, the aim of this study was to investigate the immediate effect of insole with medial longitudinal arch support and metatarsal pad on plantar pressure distribution in females with rheumatoid arthritis. Materia...
Introduction: Mutations in the BRCA1 gene are major risk factors for breast and ovarian cancers. However, the relationship between some BRCA1 mutations and cancer risk remains largely unknown. Cancer risk predictions could be improved by evaluation of the impairment degree in the BRCA1 functions due to a specific mutation. This study aimed to assess the functional effect of a novel variant (Glu...
Background: Development of safe radioprotector is a challenging task. In this study radioprotective effect of sucrose has been demonstrated in calf thymus DNA (CtDNA). Sucrose is a free radical scavenger and also acts as osmolyte and therefore can influence the water activity around DNA and effects of radiation on DNA. Hoechst 33258 was used to probe the possible alteration in physicochemical p...
abstract amino acids are building blocks of proteins, and play a vital role in living beings existence and their functionality. the interaction of these compounds with metal ions is of great importance to biochemists, and chemists, because their functions can be utilized as a model in understanding enzymes mechanism for transport of metal ions to tissues. among twenty essential amino acids w...
Effective mental sub-health early warning mechanism is of great significance in the protection of individual mental health. The traditional mental health assessment method is mainly based on questionnaire surveys, which may have some uncertainties. In this study, based on the relationship between the default mode network (DMN) and the mental health status, we proposed a human mental sub-health ...
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