Abstract Background There are few non-invasive monitoring methods that can reliably predict fluid responsiveness (FR) in children. Here, we interrogate the value of doppler ultrasound evaluation passive leg raising (PLR)-induced changes stroke volume (SV) and cardiac output (CO) as a predictor FR children with mechanical ventilation after congenital surgery. Methods A total 40 following surgery...

ACh exerted a biphasic effect in the in vitro working heart of Rana esculenta. High concentrations (10-7 M) of ACh depressed stroke volume (SV) and stroke work (SW) by ∼30% with a shorter systolic phase and reduced peak pressure. Doses from 10-10 M induced a positive response peaking at 10-8 M (SV: +8.6%; SW: +6.5%) and a prolonged systolic phase without affecting peak pressure. Atropine and pi...

Right ventricular (RV) function was studied in 13 patients under controlled mechanical ventilation with positive end-expiratory pressure (PEEP) for adult respiratory distress syndrome. The assessment of RV function was made by the thermodilution technique. Calculations of RV ejection fraction (RVEF) and RV end-diastolic volume (RVEDV) were performed. In 11 patients, increasing PEEP was accompan...

Children with sickle cell anemia (SCA) carry a 200-fold increased risk for cerebral infarction. Stroke can be the result of small-vessel (SV) or large-vessel (LV) disease. However, it is unknown whether these subtypes result from the same pathophysiologic processes. Complete HLA genotyping was performed on 231 eligible children previously enrolled in the Cooperative Study of Sickle Cell Disease...

There is at present no good understanding of the exact clinical correlates of arterial compliance. The purpose of this study was to establish which hemodynamic variables are most strongly associated with compliance. Hemodynamic measurements were performed on 41 patients undergoing diagnostic cardiac catheterization. Cardiac outputs were determined by thermodilution, and pressures were measured ...

the present study attempted to compare the structural and functional changes of left heart ventricle in female basketball players of khuzestan superior league (aged between 18 and 29) during regular training and long-term detraining. out of 30 female players, 15 subjects were assigned randomly to regular training group and 15 subjects to long-term detraining group. the structural and functional...

We developed a framework of analysis to predict the stroke volume (SV) resulting from the complex mechanical interaction between the ventricle and its arterial system. In this analysis, we characterized both the left ventricle and the arterial system by their end systolic pressure (Ps)-SV relationships and predicted SV from the intersection of the two relationship lines. The final output of the...

In this study we assessed the effects of ,3-adrenergic blockade on cardiac function during exercise. First-pass radionuclide angiography was used to measure left ventricular ejection fraction (LVEF), cardiac output (CO), end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV) and pulmonary transit time (PTT) in 12 normal young men. Studies were first performed at rest and duri...

Method Male Wistar rats (300 ± 50g) were anesthetized and, after left thoracotomy, MI was induced by ligation of left anterior descending (LAD) coronary. Sham rats were submitted only to thoracotomy. One week thereafter, MI rats were randomly submitted to left (LS) or bilateral (BS) sympathectomy by chemical ablation of stellate ganglion. Eight weeks after LAD ligation, the ventricular function...

It is important to verify the old findings of Cumming (1972) and Goldberg and Shephard (1980) who showed that stroke volume (SV) may be higher during recovery rather than during exercise, in order to organize the number of intervals throughout training sessions. The purpose of this study was to re-evaluate individual SV responses to various upright cycling exercises using the nitrous-oxide rebr...