PURPOSE Migraine and artery dissection are both rare causes of ischemic stroke. The mechanism of migraine-related intracranial artery dissection is still unknown. It is proposed that the repeated attack of migraine would make the involved artery more vulnerable to tearing and lead to dissection. CASE REPORT We describe a 42-year-old female suffering from basilar-type migraine for more than 20...

BACKGROUND There is controversy as to whether migraine is associated with white matter abnormalities (WMAs) on magnetic resonance images. These abnormalities may be important as a risk factor for future stroke. Further, it is controversial whether any increased risk of WMAs is attributable to comorbidities such as vascular disease. METHODS A meta-analysis of published case-control studies was...

BACKGROUND Migraine has been associated with risk of cardiovascular disease (CVD). Data on the association between migraine frequency and CVD are sparse. METHODS Prospective cohort study of 27,798 US women aged >or=45 years, who were free of CVD, and for whom we had information on lipids and migraine frequency. We categorized migraine frequency as < monthly, monthly, and >or= weekly. Incident...

BACKGROUND Migraine is associated with an increased risk for cardiovascular disease (CVD). Both migraine and CVD are highly heritable. However, the genetic liability for CVD among migraineurs is unclear. METHODS We performed a genome-wide association study for incident CVD events during 12 years of follow-up among 5,122 migraineurs participating in the population-based Women's Genome Health S...

1. Domitrz I, Mieszkowski J, Kaminska A. Relationship between migraine and patent foramen ovale: A study of 121 patients with migraine. Headache. 2007;47:1311-1318. 2. Gori S, Morelli N, Fanucchi S, et al. The extent of right-toleft shunt fails to correlate with severity of clinical picture in migraine with aura. Neurol Sci. 2006;27:14-17. 3. Tembl-Ferrairo JI, Lago-Martin A, Sevilla T, Bosca-B...

OBJECTIVE  To evaluate the association between migraine and incident cardiovascular disease and cardiovascular mortality in women. DESIGN  Prospective cohort study among Nurses' Health Study II participants, with follow-up from 1989 and through June 2011. SETTING  Cohort of female nurses in United States. PARTICIPANTS  115 541 women aged 25-42 years at baseline and free of angina and card...

Figure 1. The patent foramen ovale (PFO). Migraine is co-morbid with numerous other illnesses, including psychiatric disorders (depression, anxiety and bipolar disorder), epilepsy and stroke.1 Strong pathophysiological links have been identified between migraine and these conditions. Historically, migraine has also been associated with heart disease,2 but this has proved difficult to confirm.1 ...