[1] What happens in the crust as a result of geodetically observed secular motions? In this paper we find out by distorting a finite element model of California using GPS-derived displacements. A complex model was constructed using spatially varying crustal thickness, geothermal gradient, topography, and creeping faults. GPS velocity observations were interpolated and extrapolated across the mo...

See Online/Articles http://dx.doi.org/10.1016/ S0140-6736(12)61031-9 Exercise has been called a miracle drug that can benefi t every part of the body and substantially extend lifespan. Yet it receives little respect from doctors or society. Socially, being inactive is perceived as normal, and in fact doctors order patients to remain on bed rest far more often than they encourage exercise. This ...

Hepatocellular carcinoma (HCC) is the third leading cause of cancer death and the fifth most common solid tumor worldwide [1,2]. Liver tumorigenesis is a multistep process in which external stimuli such as chronic inflammation or cirrhosis lead to the development of clonal populations of dysplastic hepatocytes that accumulate genetic changes and evolve into malignant foci [2]. Among the most co...

We investigate upper plate stressing during the earthquake cycle in a subduction segment, using three-dimensional (3-D) elastic models to address the effects of strongly heterogeneous coupling along strike of the interplate interface. We show how heterogeneity controls the locations and mechanisms of seismicity in the upper plate. Oblique subduction segments, two from the Aleutians (Andreanof I...

Particle compound material is the composition of different particles with inhomogeneous and non-uniform properties. Particle compound material is the most complicated engineering material whose properties vary according to the applications, method of manufacturing and ratio of its ingredients. The quasi-homogeneous materials like building materials and constituents of tablets, pellets etc are s...

The impact of a stress scenario of default events on the loss distribution of a credit portfolio can be assessed by determining the loss distribution conditional on these events. While it is conceptually easy to estimate loss distributions conditional on default events by means of Monte Carlo simulation, it becomes impractical for two or more simultaneous defaults as then the conditioning event...