Streptococcus pneumoniae is an important human pathogen associated with pneumonia, septicaemia, meningitis and otitis media. It is estimated to result in over 3 million child deaths worldwide every year and an even greater number of deaths among the elderly. Prior to the complete sequencing of the genomes of S. pneumoniae TIGR4 (serotype 4) and S. pneumoniae R6 (serotype 2), we designed a custo...

Recovery of Streptococcus pneumoniae from positive blood culture bottles may be difficult due to autolysis of pneumococci. Therefore, we evaluated the performance of the Binax NOW S. pneumoniae antigen test with samples from positive blood culture bottles and defined the duration of detectable pneumococcal antigen in these bottles. Use of the S. pneumoniae antigen test is an alternative method ...

BACKGROUND Streptococcus pneumoniae is a leading cause of invasive bacterial disease in developed and developing countries. We studied the loop-mediated isothermal amplification (LAMP) technique to assess its suitability for detecting S. pneumoniae nucleic acid in cerebrospinal fluid (CSF). METHODOLOGY/PRINCIPAL FINDINGS We established an improved LAMP assay targeting the lytA gene (Streptoco...

Madam, this is in reference to an article titled “Antibiotic Susceptibility of Streptococcus Pneumoniae in Karachi” published in JPMA Vol. 50, No.2, February 2000. in the Results the authors have reported 100% susceptibility to amoxyci Ilin—clavulanate whereas the same isolates have 80.2% susceptibility to penicillin and the rest 19.8% are having intermediate status. These results suggest that ...

OBJECTIVES Urinary tract infection is the second most common clinical indication for empirical antibiotic treatment in primary and secondary health care settings. The incidence of diabetes mellitus throughout the world is increasing strikingly and in the long run, it has some major effects on the genitourinary system which makes diabetic patients more liable to urinary tract infection. This stu...

The following organisms have shown in vitro sensitivity to DBLTM Cefotaxime Sodium for Injection. Gram-positive: Staphylococci spp, including coagulase-positive, coagulase-negative and penicillinase-producing strains. Streptococci spp, including β-haemolytic and other streptococci such as Streptococcus mitis (viridans), Streptococcus pneumoniae. (Many strains of enterococci, e.g. Streptoco...

The incidence of secondary lung infections in hospitalized patients with COVID-19 is not well understood. results bacteriological research for nonspecific flora sputum or flushing from the respiratory tract were analyzed 820 out 3040 at Research Institute Lung Diseases Baku. Secondary microflora was detected 771 (94%) patients. 347 (42.3%) cases, fungi genus Candida found, and 211 (25.7%) this ...

Four macrolide-lincosamide-streptogramin B resistance plasmids transferred into 13 recipients belonging to Streptococcus, Staphylococcus, and Listeria genera. The plasmids were stably maintained in all new hosts except Streptococcus sanguis, Streptococcus pneumoniae, Staphylococcus aureus, and Listeria innocua and were identical to those found in the corresponding donor strains.

Streptococcus mitis has emerged as one of the leading causes of bacterial endocarditis and is related to Streptococcus pneumoniae. Antibiotic resistance has also increased among strains of S. mitis and S. pneumoniae. Phages are being reinvestigated as alternatives to antibiotics for managing infections. In this study, the two virulent phages Cp-1 (Podoviridae) and Dp-1 (Siphoviridae), previousl...

Background: To date, more than 90 Streptococcus pneumoniae (S. pneumoniae) capsular serotypes are known. The prevalence of these serotypes varies according to the geographical area and the regional vaccination program. Due to the lack of regular vaccination programs for S. pneumoniae in developing countries, serotyping of the prevalent isolates is useful in selecting the correct vaccine. The pr...