Abstract Stevia ( rebaudiana Bertoni) is a natural zero calorie sweetener with significant economic and medicinal values due to its high contents of steviosides (SVGs) in the leaves. The aqueous extract leaves (TAqE) was standardized contain 8.5% w/w SVGs (HPLC), total phenolics (164.63 ± 1.39 µg Gallic acid/mg extract) flavonoids 100.5 0.79 QE/mg extract. Twenty-one compounds were tentatively ...

The aim of this study was to analyze the optimum temperature and percentage ethanol extract steviol glycosides (Stevioside Rebaudioside A) from stevia leaves in a percolation extractor. experiments were performed broad ranges binary solvent (0-100 % ethanol) (30–70 °C) order investigate their effects on recovery purity. optimal extraction conditions, which gave best kinetic 70 °C 35% ethanol. I...

A comparative study on the potential of some biological agents to perform the hydrolysis of stevioside was carried out, aiming at establishing an alternative methodology to achieve the aglycon steviol or its rearranged derivative isosteviol, in high yields to be used in the preparation of novel bioactive compounds. Hydrolysis reactions were performed by using filamentous fungi (Aspergillus nige...

In order to improve the bioavailability of lutein (LUT), a novel lutein-stevioside nanoparticle (LUT-STE) were prepared previously, but information about LUT-STE on protecting eye health was limited. This study investigated effect antioxidant activity H2O2-induced human retinal pigment epithelial cells (ARPE) cells. LUT and (final concentration 5 μg/mL) significantly enhan...

Chen J, Jeppesen PB, Nordentoft I, Hermansen K. Stevioside improves pancreatic -cell function during glucotoxicity via regulation of acetyl-CoA carboxylase. Am J Physiol Endocrinol Metab 292: E1906 –E1916, 2007. First published March 6, 2007; doi:10.1152/ajpendo.00356.2006.—Chronic hyperglycemia is detrimental to pancreatic -cells, causing impaired insulin secretion and -cell turnover. The char...