نتایج جستجو برای: sterol content determination

تعداد نتایج: 661608  

Journal: :Journal of lipid research 2000
A J Brown E L Mander I C Gelissen L Kritharides R T Dean W Jessup

Cholesterol- and cholesteryl ester-rich macrophage foam cells, characteristic of atherosclerotic lesions, are often generated in vitro using oxidized low density lipoprotein (OxLDL). However, relatively little is known of the nature and extent of sterol deposition in these cells or of its relationship to the foam cells formed in atherosclerotic lesions. The purpose of this study was to examine ...

Journal: :Biochemical Society transactions 1975
B de Kruyff

Sterols are main constituents of many membranes. Cholesterol is the most abundant sterol in membranes of higher organisms. Many studies have been undertaken to try to understand the function of cholesterol, in which the interaction between cholesterol and various phosphatidylcholines were investigated in monolayers and liposomes (Phillips, 1972). The physicochemical state of the lipids determin...

Journal: :Antimicrobial agents and chemotherapy 1997
D W Denning K Venkateswarlu K L Oakley M J Anderson N J Manning D A Stevens D W Warnock S L Kelly

Invasive aspergillosis is an increasingly frequent opportunistic infection in immunocompromised patients. Only two agents, amphotericin B and itraconazole, are licensed for therapy. Itraconazole acts through inhibition of a P-450 enzyme undertaking sterol 14alpha demethylation. In vitro resistance in Aspergillus fumigatus to itraconazole correlated with in vivo outcome has not been previously d...

E.S. Hosseini M. Ghavami M. Homapour Z. Piravivanak

Olive oil in general due to it monounsaturation, stability, nutritive value, consistency, taste andaroma might be considered as a valuable and luxury oil. Annual importation of olive oil to Iran fromMediterranean countries is on a large scale although some olive oils are produced in Iran particularly in the northand some plantation has been applied in different provinces particularly in Fars. T...

Journal: :Evidence-based Complementary and Alternative Medicine : eCAM 2008
Louis Lippiello Joseph V. Nardo Robert Harlan Tiffany Chiou

Avocado/soy unsaponifiable (ASU) components are reported to have a chondroprotective effect by virtue of anti-inflammatory and proanabolic effects on articular chondrocytes. The identity of the active component(s) remains unknown. In general, sterols, the major component of unsaponifiable plant material have been demonstrated to be anti-inflammatory in vitro and in animal models. These studies ...

2013
Agata Maciejak Agata Leszczynska Ilona Warchol Monika Gora Joanna Kaminska Danuta Plochocka Monika Wysocka-Kapcinska Dorota Tulacz Joanna Siedlecka Ewa Swiezewska Maciej Sojka Witold Danikiewicz Norbert Odolczyk Anna Szkopinska Grazyna Sygitowicz Beata Burzynska

BACKGROUND The yeast Saccharomyces cerevisiae can be a useful model for studying cellular mechanisms related to sterol synthesis in humans due to the high similarity of the mevalonate pathway between these organisms. This metabolic pathway plays a key role in multiple cellular processes by synthesizing sterol and nonsterol isoprenoids. Statins are well-known inhibitors of 3-hydroxy-3-methylglut...

Journal: :The Journal of biological chemistry 1991
J R Jefferson J P Slotte G Nemecz A Pastuszyn T J Scallen F Schroeder

The potential role of liver fatty acid binding protein (L-FABP) in modulating cellular sterol distribution was examined in mouse L-cell fibroblasts transfected with cDNA encoding L-FABP. L-cells were chosen because they contain only a small amount of endogenous FABP which does not bind [3H]cholesterol, does not enhance intermembrane sterol transfer, and whose content is unaltered by the express...

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