Previous studies have demonstrated that normal mammary tissue contains a hierarchy of cell types that are ultimately and continuously derived from a self-sustaining mammary stem cell population. However, a suitable assay for detecting, quantifying and characterizing such cells in humans has been lacking. Here we show that histologically normal, bi-layered mammary epithelial structures containin...

This work aimed to investigate the effect of Sophora flavescens polysaccharide on proliferation and osteogenic differentiation dental pulp stem cells. The cells were isolated from rat crown tissue surface biomarkers identified by flow cytometry. was assessed alizarin red staining alkaline phosphatase staining. treated with different doses for time points cell viability counting kit 8. Cell migr...

Introduction: CSCs have been identified in prostate cancer (PCa), one of the most diagnosed malignancies in men over the world, for which radiation resistance is a major problem in the treatment of advanced stages. Cancer stem cells (CSCs) have the ability to self-renew and differentiate to give rise to heterogeneous phenotype of the tumor cells. It is believed that CSCs are ...

Objective(s) Bone marrow is the traditional source of human multipotent mesenchymal stem cells (MSCs), but adipose tissue appears to be an alternative and more readily available source. In this study, rat adipose-derived stem cells (ADSCs) were induced to differentiate into Schwann-like cells and compared with rat bone marrow stem cells (BMSCs) for their Schwann-like cells differentiation pote...

BACKGROUND Endometrial stem/progenitor cells contribute to the cyclical regeneration of human endometrium throughout a woman's reproductive life. Although the candidate cell populations have been extensively studied, no consensus exists regarding which endometrial population represents the stem/progenitor cell fraction in terms of in vivo stem cell activity. We have previously reported that hum...